PCDHAC2 antibody (Middle Region)

Catalog No. ABIN954038

The Rabbit Polyclonal anti-PCDHAC2 antibody has been validated for WB, IF, IHC (p) and EIA. It is suitable to detect PCDHAC2 in samples from Human.

Quick Overview for PCDHAC2 antibody (Middle Region) (ABIN954038)

Target: PCDHAC2 (Protocadherin alpha Subfamily C, 2 (PCDHAC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHAC2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-PCDHAC2 Antibody

Binding Specificity: AA 623-652, Middle Region

Specificity: This antibody detects human PCDHAC2.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Purified through a protein A column; followed by peptide affinity purification.

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the central region (between 623-652aa) of human PCDHAC2.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PCDHAC2

Target: PCDHAC2 (Protocadherin alpha Subfamily C, 2 (PCDHAC2))

Alternative Name: PCDHAC2

Background: The PCDHAC2 gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.Synonyms: PCDH-alpha-C2, Protocadherin alpha-C2

Gene ID: 56134

NCBI Accession: NP_061722