RPL7 antibody (N-Term)

Catalog No. ABIN954601

This Rabbit Polyclonal antibody specifically detects RPL7 in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for RPL7 antibody (N-Term) (ABIN954601)

Target: RPL7 (Ribosomal Protein L7 (RPL7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPL7 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-RPL7 Antibody

Binding Specificity: AA 5-35, N-Term

Specificity: Recognizes RPL7 (N-term).

Purification: Protein A column followed by peptide Affinity purification

Immunogen: KLH conjugated synthetic peptide between 5-35 amino acids from the N-terminal region of Human RPL7 Genename: RPL7

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for RPL7

Target: RPL7 (Ribosomal Protein L7 (RPL7))

Alternative Name: RPL7

Background: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30P family of ribosomal proteins. It contains an N-terminal basic region-leucine zipper (BZIP)-like domain and the RNP consensus submotif RNP2. In vitro the BZIP-like domain mediates homodimerization and stable binding to DNA and RNA, with a preference for 28S rRNA and mRNA. The protein can inhibit cell-free translation of mRNAs, suggesting that it plays a regulatory role in the translation apparatus. It is located in the cytoplasm. The protein has been shown to be an autoantigen in patients with systemic autoimmune diseases, such as systemic lupus erythematosus. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.Synonyms: 60S ribosomal protein L7

Gene ID: 6129

NCBI Accession: NP_000962