SDHD antibody (N-Term)

Catalog No. ABIN954695

Product Details anti-SDHD Antibody

Target: SDHD (Succinate Dehydrogenase Complex, Subunit D, Integral Membrane Protein (SDHD))

Binding Specificity: AA 20-50, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SDHD antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: Recognizes SDHD (N-term).

Purification: Protein A column followed by peptide Affinity purification

Immunogen: KLH conjugated synthetic peptide between 20-50 amino acids from the N-terminal region of Human SDHD (NP_002993.1)

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SDHD

Target: SDHD (Succinate Dehydrogenase Complex, Subunit D, Integral Membrane Protein (SDHD))

Alternative Name: SDHD (SDHD Products)

Background: Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The subunit D protein is one of two integral membrane proteins anchoring the complex to the matrix side of the membrane. Mutations in SDHD have been linked to hereditary paraganglioma.Synonyms: CII-4, CybS, QPs3, SDH4, Succinate dehydrogenase [ubiquinone] cytochrome b small subunit mitochondrial, Succinate dehydrogenase complex subunit D, Succinate-ubiquinone oxidoreductase cytochrome b small subunit, Succinate-ubiquinone reductase membrane anchor subunit

Gene ID: 6392

NCBI Accession: NP_002993