SDHD antibody (AA 13-42)

Catalog No. ABIN3032766

The Rabbit Polyclonal anti-SDHD antibody (ABIN3032766) specifically detects SDHD in WB, IHC, ELISA, IF and FACS. The antibody is reactive with Human samples.

Quick Overview for SDHD antibody (AA 13-42) (ABIN3032766)

Target: SDHD (Succinate Dehydrogenase Complex, Subunit D, Integral Membrane Protein (SDHD))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SDHD antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-SDHD Antibody

Binding Specificity: AA 13-42

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 13-42 from the human protein was used as the immunogen for this SDHD antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the SDHD antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the SDHD antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for SDHD

Target: SDHD (Succinate Dehydrogenase Complex, Subunit D, Integral Membrane Protein (SDHD))

Alternative Name: SDHD

Background: Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The subunit D protein is one of two integral membrane proteins anchoring the complex to the matrix side of the membrane. Mutations in SDHD have been linked to hereditary paraganglioma.

UniProt: O14521