TNKS antibody (N-Term)

Catalog No. ABIN955072

This Rabbit Polyclonal antibody specifically detects TNKS in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for TNKS antibody (N-Term) (ABIN955072)

Target: TNKS (Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNKS antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-TNKS Antibody

Binding Specificity: AA 54-82, N-Term

Specificity: This antibody detects Tankyrase-1 (TANK1) (N-term).

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 54-82 amino acids from the N-terminal region of human TNKS

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Target Details for TNKS

Target: TNKS (Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS))

Alternative Name: Tankyrase-1 (TANK1)

Background: TNKS may regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. Has PARP activity and can modify TERF1, and thereby contribute to the regulation of telomere length.Synonyms: PARP5A, PARPL, TIN1, TINF1, TNKS, TNKS-1, TNKS1, TRF1-interacting ankyrin-related ADP-ribose polymerase, Tankyrase I

Gene ID: 8658

NCBI Accession: NP_003738