TMLHE antibody (N-Term)

Catalog No. ABIN955260

Product Details anti-TMLHE Antibody

Target: TMLHE (Trimethyllysine Hydroxylase, epsilon (TMLHE))

Binding Specificity: AA 123-153, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMLHE antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects TMLHE / TMLD (N-term).

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 123-153 amino acids from the N-terminal region of human TMLHE

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Target Details for TMLHE

Target: TMLHE (Trimethyllysine Hydroxylase, epsilon (TMLHE))

Alternative Name: TMLHE / TMLD (TMLHE Products)

Background: This gene encodes the protein trimethyllysine dioxygenase which is the first enzyme in the carnitine biosynthesis pathway. Carnitine play an essential role in the transport of activated fatty acids across the inner mitochondrial membrane. The encoded protein converts trimethyllysine into hydroxytrimethyllysine. A pseudogene of this gene is found on chromosome X. Alternate splicing results in multiple transcript variants.Synonyms: Epsilon-trimethyllysine 2-oxoglutarate dioxygenase, TML dioxygenase, TML hydroxylase, TML-alpha-ketoglutarate dioxygenase, TMLH, Trimethyllysine dioxygenase mitochondrial

Gene ID: 55217

NCBI Accession: NP_001171726