TRAF4 antibody (C-Term)

Catalog No. ABIN955308

This anti-TRAF4 antibody is a Rabbit Polyclonal antibody detecting TRAF4 in WB and EIA. Suitable for Human.

Quick Overview for TRAF4 antibody (C-Term) (ABIN955308)

Target: TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRAF4 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-TRAF4 Antibody

Binding Specificity: AA 426-455, C-Term

Specificity: This antibody detects TRAF4 / RNF83 (C-term).

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 426-455 amino acids from the C-terminal region of human TRAF4

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Target Details for TRAF4

Target: TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))

Alternative Name: TRAF4 / RNF83

Background: This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined.Synonyms: CART1, Cysteine-rich domain associated with RING and Traf domains protein 1, MLN62, Malignant 62, RING finger protein 83, TNF receptor-associated factor 4

Gene ID: 9618

NCBI Accession: NP_004286