ASPM antibody (Internal Region)

Catalog No. ABIN960544

This Rabbit Polyclonal antibody specifically detects ASPM in IHC and IHC (p). It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for ASPM antibody (Internal Region) (ABIN960544)

Target: ASPM (Asp (Abnormal Spindle) Homolog, Microcephaly Associated (ASPM))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASPM antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ASPM Antibody

Binding Specificity: Internal Region

Brand: IHC-plus™

Specificity: Recognizes human ASPM. Species cross-reactivity: rat. Sequence homology: chimpanzee, primate.

Purification: Affinity purified

Immunogen: Synthetic peptide corresponding to human ASPM (KLH).

Type of Immunogen: Synthetic peptide - KLH conjugated

Isotype: IgG

Application Details

Application Notes: Approved: IHC, IHC-P (5 μg/mL)

Usage: Suitable for use in Western Blot (1:300) and Immunohistochemistry.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.1 M Tris-glycine,  pH 7.4, 150 mM sodium chloride, 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Aliquot to Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.

References for anti-ASPM antibody (ABIN960544)

Lin, Liang, Dong, Ren, Zhao, Li: "Identification of Abnormal Spindle Microtubule Assembly as a Promising Therapeutic Target for Osteosarcoma." in: Orthopaedic surgery, Vol. 12, Issue 6, pp. 1963-1970, (2021) (PubMed).

Yuan, Sun, Gao, Yin, Yuan, Xu: "Abnormal spindle-like microcephaly-associated protein (ASPM) contributes to the progression of Lung Squamous Cell Carcinoma (LSCC) by regulating CDK4." in: Journal of Cancer, Vol. 11, Issue 18, pp. 5413-5423, (2020) (PubMed).

Target Details for ASPM

Target: ASPM (Asp (Abnormal Spindle) Homolog, Microcephaly Associated (ASPM))

Alternative Name: ASPM

Background: Name/Gene ID: ASPM

Synonyms: ASPM, Asp homolog, Calmbp1, MCPH5, ASP

Gene ID: 259266

UniProt: Q8IZT6