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Interleukin 1 delta (FIL1d) antibody Primary Antibody

FIL1d Reactivity: Cow ELISA, WB Host: Rabbit Polyclonal
Catalog No. ABIN964734
$613.50
Plus shipping costs $45.00
100 μg ABIN964734
100 μg ABIN964734
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  • Target
    Reactivity
    Cow
    Host
    Rabbit
    Clonality
    Polyclonal
    Conjugate
    Un-conjugated
    Application
    ELISA, Western Blotting (WB)
    Specificity
    This product was Protein-A purified from monospecific antiserum by chromatography. This antibody is specific for bovine IL-1F5 protein. A BLAST analysis was used to suggest cross-reactivity with IL-1F5 from dog and mouse sources based on 94% homology with the immunizing sequence. Partial reactivity is expected against horse based on 91% homology, and to human, chimpanzee, macaque, and rat based on 90% homology with the immunizing sequence.
    Characteristics
    Interleukin-1F5 is a recently discovered cytokine which was shown to specifically inhibit the activation of NF-kappaB induced by interleukin 1 family, member 6 (IL1F6) in humans. There is very little published regarding the bovine IL1F5 protein. In the human, this gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Expression of the gene appears to be restricted to various epithelial cell populations. Costelloe et al (2008) have identified SIGIRR [single immunoglobulin domain-containing IL1R-related protein] as a receptor for human IL1F5. Anti-IL-1F5 antibody antibody is ideal for investigators involved in Signal Transduction and Immunology research.
    Sterility
    Sterile filtered
    Immunogen
    This protein-A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein raised in yeast, corresponding to the 155 amino acids of the mature bovine IL-1F5 protein.
    Immunogen Type: RecombinantProtein
    Isotype
    IgG
  • Target
    Alternative Name
    IL-1F5 (FIL1d Antibody Abstract)
    Background
    Interleukin-1F5 is a recently discovered cytokine which was shown to specifically inhibit the activation of NF-kappaB induced by interleukin 1 family, member 6 (IL1F6) in humans. There is very little published regarding the bovine IL1F5 protein. In the human, this gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Expression of the gene appears to be restricted to various epithelial cell populations. Costelloe et al (2008) have identified SIGIRR [single immunoglobulin domain-containing IL1R-related protein] as a receptor for human IL1F5. Anti-IL-1F5 antibody antibody is ideal for investigators involved in Signal Transduction and Immunology research.
    Synonyms: Interleukin 1 family, member 5 (Delta) . In humans it is also known as: IL1RP3, Il1hy1, Il-1h3, MGC29840, FIL1(DELTA), IL1F5, Il1f5, IL1L1, Fil1delta, IL1HY1, FIL1D, FIL1, or AI413231.
    Gene ID
    518514, 115494990
    UniProt
    Q0VC52
  • Application Notes
    This protein-A purified antibody is suitable for ELISA and Western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 17.1 kDa in size corresponding to bovine IL-1F5 protein by western blotting in the appropriate cell lysate or extract.
    Comment

    Gene Name: IL1F5

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitution Buffer: Restore with deionized water (or equivalent), Reconstitution Volume: 100 µL
    Concentration
    1.0 µg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
    Expiry Date
    12 months
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