Apolipoprotein M antibody

Catalog No. ABIN965578

This Monoclonal antibody specifically detects Apolipoprotein M in WB, ELISA and IF. It exhibits reactivity toward Human and has been mentioned in 3+ publications.

Quick Overview for Apolipoprotein M antibody (ABIN965578)

Target: Apolipoprotein M (APOM)

Reactivity: Human

Host: Please inquire

Clonality: Monoclonal

Conjugate: This Apolipoprotein M antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-Apolipoprotein M Antibody

Specificity: TRX purified full length recombinant ApoM-GST expressed in E. Coli strain BL21 (DE3).

Purification: Antibodies are purified by protein A affinity chromatography

Isotype: IgG2a

Application Details

Application Notes: Western Blot: 1: 500- 1: 1,000
IF: 1: 200- 1: 1,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: -20 °C

References for anti-Apolipoprotein M antibody (ABIN965578)

Wolfrum, Poy, Stoffel: "Apolipoprotein M is required for prebeta-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis." in: Nature medicine, Vol. 11, Issue 4, pp. 418-22, (2005) (PubMed).

Zhang, Jiao, Hurtig, Dong, Zheng, Luo, Nilsson-Ehle, Ye, Xu: "Expression pattern of apolipoprotein M during mouse and human embryogenesis." in: Acta histochemica, Vol. 106, Issue 2, pp. 123-8, (2004) (PubMed).

Xu, Dahlbäck: "A novel human apolipoprotein (apoM)." in: The Journal of biological chemistry, Vol. 274, Issue 44, pp. 31286-90, (1999) (PubMed).

Target Details for Apolipoprotein M

Target: Apolipoprotein M (APOM)

Alternative Name: ApoM

Background: Apolipoprotein M (ApoM) is a member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. It is positively related to leptin. It is mainly expressed in liver and kidney. ApoM is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. It is important for the formation of prebeta-HDL and cholesterol efflux to HDL, and thereby inhibits formation of atherosclerotic lesions.

Gene ID: 55937