ARL1 antibody (N-Term)

Catalog No. ABIN965592

This anti-ARL1 antibody is a Rabbit Polyclonal antibody detecting ARL1 in IHC. Suitable for Human, Mouse and Rat. This Primary Antibody has been cited in 2+ publications.

Quick Overview for ARL1 antibody (N-Term) (ABIN965592)

Target: ARL1 (ADP Ribosylation Factor Like GTPase 1 (ARL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARL1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-ARL1 Antibody

Binding Specificity: N-Term

Purification: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human ARL1(ADP-ribosylation factor-like protein 1)

Application Details

Application Notes: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-ARL1 antibody (ABIN965592)

Van Valkenburgh, Shern, Sharer, Zhu, Kahn: "ADP-ribosylation factors (ARFs) and ARF-like 1 (ARL1) have both specific and shared effectors: characterizing ARL1-binding proteins." in: The Journal of biological chemistry, Vol. 276, Issue 25, pp. 22826-37, (2001) (PubMed).

Hong, Lee, Patton, Lin, Moss, Vaughan: "Phospholipid- and GTP-dependent activation of cholera toxin and phospholipase D by human ADP-ribosylation factor-like protein 1 (HARL1)." in: The Journal of biological chemistry, Vol. 273, Issue 25, pp. 15872-6, (1998) (PubMed).

Target Details for ARL1

Target: ARL1 (ADP Ribosylation Factor Like GTPase 1 (ARL1))

Alternative Name: ARL1

Background: ARL1(ADP-ribosylation factor-like protein 1) belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, regulate intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. Although, ARL proteins were initially thought not to activate CT or PLD, later work showed that they are weak stimulators of PLD and CT in a phospholipid dependent manner. Recent data show that Arl1 regulates the membrane recruitment of Golgin-97, which plays a role in transport from the endosome to the trans-Golgi network.