BNP antibody

Catalog No. ABIN965691

This anti-BNP antibody is a Mouse Monoclonal antibody detecting BNP in IHC and ELISA. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for BNP antibody (ABIN965691)

Target: BNP (Brain Natriuretic Peptide (BNP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BNP antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Clone: 3A6F7C7

Product Details anti-BNP Antibody

Purification: Ascitic fluid

Immunogen: Synthetic peptide corresponding to aa (Glu-Pro-Leu-Gln-Glu-Ser-Pro-Arg-Pro-Thr-Gly-Val-Trp-Cys) of human BNP, conjugated to KLH.

Isotype: IgG1

Application Details

Application Notes: Immunohistochemistry: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References for anti-BNP antibody (ABIN965691)

Pfister, Erdmann, Schneider: "[Natriuretic peptides BNP and NT-pro-BNP--the "new troponins" for estimation of heart failure?]." in: Deutsche medizinische Wochenschrift (1946), Vol. 128, Issue 18, pp. 1007-12, (2003) (PubMed).

Target Details for BNP

Target: BNP (Brain Natriuretic Peptide (BNP))

Alternative Name: BNP

Background: BNP (brain natriuretic peptide) belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C-type natriuretic peptide (CNP) and urodilatin. ANP and BNP act mainly as cardiac hormones, produced primarily by the atrium and ventricle, respectively, while the gene encoding C-type natriuretic peptide is expressed mainly in the brain. BNP circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. It is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. This ring structure shows high homology between different natriuretic.
Synonyms: BNP, NPPB

Gene ID: 4879

Pathways: Hormone Activity