FOXP3 antibody

Catalog No. ABIN966164

The Mouse Monoclonal anti-FOXP3 antibody has been validated for WB and ELISA. It is suitable to detect FOXP3 in samples from Human. There is 1 publication available.

Quick Overview for FOXP3 antibody (ABIN966164)

Target: FOXP3 (Forkhead Box P3 (FOXP3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FOXP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 4C7

Product Details anti-FOXP3 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human FOXP3 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References for anti-FOXP3 antibody (ABIN966164)

Yuan, Chen, Li, Dong, Xue, Wang, Zhang, Wang, Zhang, Ge, Shen, Xu: "Elevated expression of Foxp3 in tumor-infiltrating Treg cells suppresses T-cell proliferation and contributes to gastric cancer progression in a COX-2-dependent manner." in: Clinical immunology (Orlando, Fla.), Vol. 134, Issue 3, pp. 277-88, (2010) (PubMed).

Target Details for FOXP3

Target: FOXP3 (Forkhead Box P3 (FOXP3))

Alternative Name: FOXP3

Background: FOXP3 (a 431 amino acid protein) is a member of the forkhead/winged-helix family of transcriptional regulators and is highly conserved across mammals. FOXP3 is essential for normal immune homeostasis. FOXP3 is stably and
Synonyms: JM2, AIID, IPEX, PIDX, XPID, DIETER, MGC141961, MGC141963, FOXP3

Molecular Weight: 47.2kDa

Gene ID: 50943

Pathways: Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation