APOA4 antibody (AA 21-396)

Catalog No. ABIN968959

This Mouse Monoclonal antibody specifically detects APOA4 in WB and ELISA. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for APOA4 antibody (AA 21-396) (ABIN968959)

Target: APOA4 (Apolipoprotein A-IV (APOA4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This APOA4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 2D1C9

Product Details anti-APOA4 Antibody

Binding Specificity: AA 21-396

Purpose: APOA4 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of APOA4 (aa21-396) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-APOA4 antibody (ABIN968959)

Chien, Chen, Hsu, Su, Chang, Lee, Lee: "Genetic association study of APOA1/C3/A4/A5 gene cluster and haplotypes on triglyceride and HDL cholesterol in a community-based population." in: Clinica chimica acta; international journal of clinical chemistry, Vol. 388, Issue 1-2, pp. 78-83, (2007) (PubMed).

Peignon, Thenet, Schreider, Fouquet, Ribeiro, Dussaulx, Chambaz, Cardot, Pinçon-Raymond, Le Beyec: "E-cadherin-dependent transcriptional control of apolipoprotein A-IV gene expression in intestinal epithelial cells: a role for the hepatic nuclear factor 4." in: The Journal of biological chemistry, Vol. 281, Issue 6, pp. 3560-8, (2006) (PubMed).

Target Details for APOA4

Target: APOA4 (Apolipoprotein A-IV (APOA4))

Alternative Name: APOA4

Background: APOA4: apolipoprotein A-IV. Apoliprotein (apo) A-IV gene contains 3 exons separated by two introns. A sequence polymorphism has been identified in the 3'UTR of the third exon. The primary translation product is a 396-residue preprotein which after proteolytic processing is secreted its primary site of synthesis, the intestine, in association with chylomicron particles. Although its precise function is not known, apo A-IV is a potent activator of lecithin-cholesterol acyltransferase in vitro.

Molecular Weight: 45 kDa

Gene ID: 337

UniProt: P06727

Pathways: Lipid Metabolism