APOL1 antibody

Catalog No. ABIN968963

Product Details anti-APOL1 Antibody

Target: APOL1 (Apolipoprotein L, 1 (APOL1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This APOL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: APOL1 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of APOL1 expressed in E. Coli.

Clone: 1D4

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-APOL1 antibody (ABIN968963)

Vanhollebeke, Nielsen, Watanabe, Truc, Vanhamme, Nakajima, Moestrup, Pays: "Distinct roles of haptoglobin-related protein and apolipoprotein L-I in trypanolysis by human serum." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 10, pp. 4118-23, (2007) (PubMed).

Albert, Duchateau, Deeb, Pullinger, Cho, Heilbron, Malloy, Kane, Brown: "Apolipoprotein L-I is positively associated with hyperglycemia and plasma triglycerides in CAD patients with low HDL." in: Journal of lipid research, Vol. 46, Issue 3, pp. 469-74, (2005) (PubMed).

Target Details for APOL1

Target: APOL1 (Apolipoprotein L, 1 (APOL1))

Alternative Name: APOL1 (APOL1 Products)

Background: APOL1(apolipoprotein L, 1), also known as APOL, APO-L, APOL-I. Entrez Protein NP_001130012. It is a 395aa secreted high density lipoprotein which binds to apolipoprotein A-I. And is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. The apolipoprotein L gene family encodes six highly homologous proteins designated apoL-I to -VI. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 44 kDa

Gene ID: 8542

UniProt: O14791