Calnexin antibody
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- Target See all Calnexin (CANX) Antibodies
- Calnexin (CANX)
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Calnexin antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
- Purpose
- Calnexin Antibody
- Sequence
- CEAAEERPWL WVVYILTVAL
- Purification
- Ascitic fluid
- Immunogen
- Synthetic peptide corresponding to aa (CEAAEERPWLWVVYILTVAL) of human Calnexin, conjugated to KLH.
- Clone
- 3H4A7
- Isotype
- IgG2b
- Top Product
- Discover our top product CANX Primary Antibody
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- Application Notes
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ELISA: 1/10000
ICC: 1/200 - 1/1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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The low-density lipoprotein receptor-related protein associates with calnexin, calreticulin, and protein disulfide isomerase in receptor-associated-protein-deficient fibroblasts." in: Experimental cell research, Vol. 294, Issue 1, pp. 244-53, (2004) (PubMed).
: "Curcumin, a major constituent of turmeric, corrects cystic fibrosis defects." in: Science (New York, N.Y.), Vol. 304, Issue 5670, pp. 600-2, (2004) (PubMed).
: "EDEM as an acceptor of terminally misfolded glycoproteins released from calnexin." in: Science (New York, N.Y.), Vol. 299, Issue 5611, pp. 1394-7, (2003) (PubMed).
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The low-density lipoprotein receptor-related protein associates with calnexin, calreticulin, and protein disulfide isomerase in receptor-associated-protein-deficient fibroblasts." in: Experimental cell research, Vol. 294, Issue 1, pp. 244-53, (2004) (PubMed).
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- Target
- Calnexin (CANX)
- Alternative Name
- Calnexin (CANX Products)
- Background
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Description: This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described.
Aliases: CNX, P90, CANX
- Molecular Weight
- 90kDa
- Gene ID
- 821
- HGNC
- 821
- UniProt
- P27824
- Pathways
- MAPK Signaling, Thyroid Hormone Synthesis
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