ETV1 antibody (AA 1-191)

Catalog No. ABIN969120

This anti-ETV1 antibody is a Mouse Monoclonal antibody detecting ETV1 in ELISA. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for ETV1 antibody (AA 1-191) (ABIN969120)

Target: ETV1 (Ets Variant 1 (ETV1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ETV1 antibody is un-conjugated

Application: ELISA

Clone: 1C8B6

Product Details anti-ETV1 Antibody

Binding Specificity: AA 1-191

Purpose: ETV1 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of ETV1 (aa1-191) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-ETV1 antibody (ABIN969120)

Cerveira, Ribeiro, Peixoto, Costa, Henrique, Jerónimo, Teixeira: "TMPRSS2-ERG gene fusion causing ERG overexpression precedes chromosome copy number changes in prostate carcinomas and paired HGPIN lesions." in: Neoplasia (New York, N.Y.), Vol. 8, Issue 10, pp. 826-32, (2006) (PubMed).

Target Details for ETV1

Target: ETV1 (Ets Variant 1 (ETV1))

Alternative Name: ETV1

Background: ETV1: ets variant gene 1. Several members of the Ets gene family encode sequence-specific DNA binding proteins that recognize DNA sequences with a centrally located 5'-GGAA-3' element. All of the Ets proteins recognize the same central core sequence but each protein interacts with unique sequences that flank this core. ER81 (also designated ETV1) binds the motif 5'-CGGAA/T-3'. ER81 is highly expressed in brain, testis, lung and heart. ER81 is also moderately expressed in spleen, pancreas, colon and small intestine. During development, ER81 displays a unique expression patterns which suggests that this transcriptional factor might play an important role in organogenesis. ERK-1 activates ER81 transcriptional activity while MAPKAP kinase 2 inhibits ER81.

Gene ID: 2115

UniProt: P50549