ETV5 antibody

Catalog No. ABIN969122

The Mouse Monoclonal anti-ETV5 antibody has been validated for WB and ELISA. It is suitable to detect ETV5 in samples from Human. There are 4+ publications available.

Quick Overview for ETV5 antibody (ABIN969122)

Target: ETV5 (Ets Variant 5 (ETV5))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ETV5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 3H3

Product Details anti-ETV5 Antibody

Purpose: ETV5 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human ETV5 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-ETV5 antibody (ABIN969122)

Hotta, Nakamura, Nakamura, Matsuo, Nakata, Kamohara, Miyatake, Kotani, Komatsu, Itoh, Mineo, Wada, Masuzaki, Yoneda, Nakajima, Funahashi, Miyazaki, Tokunaga, Kawamoto, Ueno, Hamaguchi, Tanaka, Yamada et al.: "Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population. ..." in: Journal of human genetics, Vol. 54, Issue 12, pp. 727-31, (2009) (PubMed).

Xie, Yin, Wang, Liu, Elashoff, Black, Koeffler: "Levels of expression of CYR61 and CTGF are prognostic for tumor progression and survival of individuals with gliomas." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 10, Issue 6, pp. 2072-81, (2004) (PubMed).

Chotteau-Lelièvre, Révillion, Lhotellier, Hornez, Desbiens, Cabaret, de Launoit, Peyrat: "Prognostic value of ERM gene expression in human primary breast cancers." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 10, Issue 21, pp. 7297-303, (2004) (PubMed).

Urzainqui, Serrador, Viedma, Yáñez-Mó, Rodríguez, Corbí, Alonso-Lebrero, Luque, Deckert, Vázquez, Sánchez-Madrid: "ITAM-based interaction of ERM proteins with Syk mediates signaling by the leukocyte adhesion receptor PSGL-1." in: Immunity, Vol. 17, Issue 4, pp. 401-12, (2002) (PubMed).

Target Details for ETV5

Target: ETV5 (Ets Variant 5 (ETV5))

Alternative Name: ETV5

Background: ETS variant 5,transcription factor of the ETS family,divergent member of the winged helix-turn-helix superfamily,expressed in brain,placenta and other tissues involved in development. Tissue specificity: Ubiquitous. ERM is expressed in Sertoli cells and spermatogonial stem cells (SSCs). Studies on knockout mice have shown that it is required for SSC self-renewal but not differentiation, thus affected mice exhibit progressive germ cell depletion.

Molecular Weight: 58 kDa

Gene ID: 2119

UniProt: P41161

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development