c-FOS antibody

Catalog No. ABIN969150

This anti-c-FOS antibody is a Mouse Monoclonal antibody detecting c-FOS in WB, ELISA, IHC and FACS. Suitable for Human. This Primary Antibody has been cited in 2+ publications.

Quick Overview for c-FOS antibody (ABIN969150)

Target: c-FOS (c-Fos) (c-Fos)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This c-FOS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 2G2

Product Details anti-c-FOS Antibody

Purpose: FOS Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human FOS expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-c-FOS antibody (ABIN969150)

Das, Muniyappa: "c-Jun-NH2 terminal kinase (JNK)-mediates AP-1 activation by thioredoxin: phosphorylation of cJun, JunB, and Fra-1." in: Molecular and cellular biochemistry, Vol. 337, Issue 1-2, pp. 53-63, (2010) (PubMed).

Wang, Sun, Jiang, Zhang, Wolfl: "FOS proliferating network construction in early colorectal cancer (CRC) based on integrative significant function cluster and inferring analysis." in: Cancer investigation, Vol. 27, Issue 8, pp. 816-24, (2009) (PubMed).

Target Details for c-FOS

Target: c-FOS (c-Fos) (c-Fos)

Alternative Name: FOS

Background: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.

Molecular Weight: 40.7 kDa

Gene ID: 2353

UniProt: P01100

Pathways: S100 Proteins