FOXA2 antibody

Catalog No. ABIN969151

This Mouse Monoclonal antibody specifically detects FOXA2 in WB, ELISA and IHC. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for FOXA2 antibody (ABIN969151)

Target: FOXA2 (Forkhead Box A2 (FOXA2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FOXA2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 7H4B7

Product Details anti-FOXA2 Antibody

Purpose: FOXA2 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of FOXA2 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-FOXA2 antibody (ABIN969151)

Halmos, Bassères, Monti, DAló, Dayaram, Ferenczi, Wouters, Huettner, Golub, Tenen: "A transcriptional profiling study of CCAAT/enhancer binding protein targets identifies hepatocyte nuclear factor 3 beta as a novel tumor suppressor in lung cancer." in: Cancer research, Vol. 64, Issue 12, pp. 4137-47, (2004) (PubMed).

Target Details for FOXA2

Target: FOXA2 (Forkhead Box A2 (FOXA2))

Alternative Name: FOXA2

Background: FOXA2 (forkhead box A2), also known as HNF3B (hepatocyte nuclear factor 3, beta). It is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. FOXA2 has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for FOXA2.

Molecular Weight: 48 kDa

UniProt: Q9Y261

Pathways: Dopaminergic Neurogenesis, Regulation of Carbohydrate Metabolic Process