HSP90AB1 antibody

Catalog No. ABIN969202

Product Details anti-HSP90AB1 Antibody

Target: HSP90AB1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class B Member 1 (HSP90AB1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HSP90AB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Purpose: HSP90AB1 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human HSP90AB1 expressed in E. Coli.

Clone: 5G4

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-HSP90AB1 antibody (ABIN969202)

Zhang, Li, Yu, Zou, Jiang, Sun: "Characterization of celastrol to inhibit hsp90 and cdc37 interaction." in: The Journal of biological chemistry, Vol. 284, Issue 51, pp. 35381-9, (2009) (PubMed).

Target Details for HSP90AB1

Target: HSP90AB1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class B Member 1 (HSP90AB1))

Alternative Name: HSP90AB1 (HSP90AB1 Products)

Background:

Description: HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. There are 2 major cytosolic HSP90 proteins, HSP90AA1 (MIM 140571), an inducible form, and HSP90AB1, a constitutive form.

Aliases: HSPC2, HSPCB, D6S182, HSP90B, FLJ26984, HSP90-BETA

Molecular Weight: 84kDa

Gene ID: 3326

HGNC: 3326

UniProt: P08238

Pathways: Regulation of Cell Size