KLF4 antibody (AA 2-470)

Catalog No. ABIN969239

The Mouse Monoclonal anti-KLF4 antibody has been validated for ELISA and IHC. It is suitable to detect KLF4 in samples from Human. There are 2+ publications available.

Quick Overview for KLF4 antibody (AA 2-470) (ABIN969239)

Target: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KLF4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Clone: 1E5

Product Details anti-KLF4 Antibody

Binding Specificity: AA 2-470

Purpose: KLF4 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human KLF4 (AA: 2-470) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-KLF4 antibody (ABIN969239)

Godmann, Gashaw, Eildermann, Schweyer, Bergmann, Skotheim, Behr: "The pluripotency transcription factor Krüppel-like factor 4 is strongly expressed in intratubular germ cell neoplasia unclassified and seminoma." in: Molecular human reproduction, Vol. 15, Issue 8, pp. 479-88, (2009) (PubMed).

Martinez-Fernandez, Nelson, Yamada, Reyes, Alekseev, Perez-Terzic, Ikeda, Terzic: "iPS programmed without c-MYC yield proficient cardiogenesis for functional heart chimerism." in: Circulation research, Vol. 105, Issue 7, pp. 648-56, (2009) (PubMed).

Target Details for KLF4

Target: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Alternative Name: KLF4

Background: Kruppel-like factor 4 (gut),endothelial Kruppel-like zinc finger protein. May act as a transcriptional activator. Binds the CACCC core sequence. May be involved in the differentiation of epithelial cells and may also function in the development of the skeleton and kidney. KLF4 is highly expressed in the epithelial cells of the skin and the gastrointestinal tract.

Molecular Weight: 55 kDa

Gene ID: 9314

UniProt: O43474

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance