Lipoprotein Lipase antibody

Catalog No. ABIN969262

This Mouse Monoclonal antibody specifically detects Lipoprotein Lipase in WB and ELISA. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for Lipoprotein Lipase antibody (ABIN969262)

Target: Lipoprotein Lipase (LPL)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Lipoprotein Lipase antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 2C5

Product Details anti-Lipoprotein Lipase Antibody

Purpose: LPL Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of LPL expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-Lipoprotein Lipase antibody (ABIN969262)

Chen, Jou, Fann, Chen, Chung, Lin, Wu, Kang, Chen, Jong, Lo, Kang, Chen, Chang, Huang, Wu, Pan: "Lipoprotein lipase variants associated with an endophenotype of hypertension: hypertension combined with elevated triglycerides." in: Human mutation, Vol. 30, Issue 1, pp. 49-55, (2009) (PubMed).

Berk, Johnson, Lee, Zhang, Boozer, Pi-Sunyer, Fried, Albu: "Higher post-absorptive skeletal muscle LPL activity in African American vs. non-Hispanic White pre-menopausal women." in: Obesity (Silver Spring, Md.), Vol. 16, Issue 1, pp. 199-201, (2008) (PubMed).

Target Details for Lipoprotein Lipase

Target: Lipoprotein Lipase (LPL)

Alternative Name: LPL

Background: LPL: lipoprotein lipase, also known as LIPD, HDLCQ11. Entrez Protein: NP_000228. It is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism.

Molecular Weight: 53.1 kDa

UniProt: P06858

Pathways: Lipid Metabolism