MSX1 antibody

Catalog No. ABIN969296

The Mouse Monoclonal anti-MSX1 antibody has been validated for WB and ELISA. It is suitable to detect MSX1 in samples from Human. There are 2+ publications available.

Quick Overview for MSX1 antibody (ABIN969296)

Target: MSX1 (Msh Homeobox 1 (MSX1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MSX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 5D11

Product Details anti-MSX1 Antibody

Purpose: MSX1 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human MSX1 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-MSX1 antibody (ABIN969296)

Mizokami, Egashira, Takekoshi, Itoh, Itoh, Osamura, Matsumae: "Expression of MSX1 in human normal pituitaries and pituitary adenomas." in: Endocrine pathology, Vol. 19, Issue 1, pp. 54-61, (2009) (PubMed).

Li, Cui, Fang, Mei: "[A novel mutation of MSX1 gene in a Chinese pedigree with oligodontia]." in: Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology, Vol. 43, Issue 3, pp. 157-9, (2008) (PubMed).

Target Details for MSX1

Target: MSX1 (Msh Homeobox 1 (MSX1))

Alternative Name: MSX1

Background: Drosophila,muscle segment (msh) homolog 1,homeo domain encoding gene,inhibiting MYOD1 expression,highly expressed in dental mesenchyme during critical bud stage,involved in epithelial-mesenchymal signaling in many organs,and in the pathogenesis of cleft lip and palate,interacting with MSX2 in mouse limb bud patterning .This gene encodes a member of the muscle segment homeobox gene family. The encoded protein functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins. It may also have roles in limb-pattern formation, craniofacial development, particularly odontogenesis, and tumor growth inhibition.Tissue specificity: Expressed in the developing nail bed mesenchyme.

Molecular Weight: 31 kDa

Gene ID: 4487

UniProt: P28360

Pathways: Regulation of Muscle Cell Differentiation, Positive Regulation of Response to DNA Damage Stimulus