PODXL antibody

Catalog No. ABIN969356

The Mouse Monoclonal anti-PODXL antibody has been validated for WB, IHC, ELISA and FACS. It is suitable to detect PODXL in samples from Human. There is 1 publication available.

Quick Overview for PODXL antibody (ABIN969356)

Target: PODXL (Podocalyxin-Like (PODXL))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PODXL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Clone: 5F5

Product Details anti-PODXL Antibody

Purpose: PODXL Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human PODXL expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-PODXL antibody (ABIN969356)

Thomas, Schnaar, Konstantopoulos: "Podocalyxin-like protein is an E-/L-selectin ligand on colon carcinoma cells: comparative biochemical properties of selectin ligands in host and tumor cells." in: American journal of physiology. Cell physiology, Vol. 296, Issue 3, pp. C505-13, (2009) (PubMed).

Target Details for PODXL

Target: PODXL (Podocalyxin-Like (PODXL))

Alternative Name: PODXL

Background: This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin. (provided by RefSeq)Tissue specificity: Glomerular epithelium cell (podocyte)

Molecular Weight: 49 kDa

UniProt: O00592

Pathways: Tube Formation