PTK6 antibody

Catalog No. ABIN969373

This Mouse Monoclonal antibody specifically detects PTK6 in WB and ELISA. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for PTK6 antibody (ABIN969373)

Target: PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PTK6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 2H12B8

Product Details anti-PTK6 Antibody

Purpose: PTK6 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human PTK6 expressed in E. Coli.

Isotype: IgG2b

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-PTK6 antibody (ABIN969373)

Park, Lee, Lee: "Characterization of the human full-length PTK7 cDNA encoding a receptor protein tyrosine kinase-like molecule closely related to chick KLG." in: Journal of biochemistry, Vol. 119, Issue 2, pp. 235-9, (1997) (PubMed).

Target Details for PTK6

Target: PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

Alternative Name: PTK6

Background: PTK6 (protein tyrosine kinase 6, BRK or FLJ42088), with 451-amino acid protein (about 52 kDa), encods a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Its presence in the nucleus appears to be linked to suppression of tumor progression. The encoded protein has been shown to undergo autophosphory-lation. Very high level in colon and high levels in small intestine and prostate, and low levels in some fetal tissues. And Expressed at low level in some breast tumors, but not in normal breast. Also found in melanocytes, but not expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype.

Molecular Weight: 52 kDa

Gene ID: 5753

UniProt: Q13882