SPI1 antibody (AA 124-271)
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- Target See all SPI1 Antibodies
- SPI1 (Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1))
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Binding Specificity
- AA 124-271
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This SPI1 antibody is un-conjugated
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Application
- ELISA, Flow Cytometry (FACS)
- Purpose
- SPI1 Antibody
- Purification
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human SPI1 (AA: 124-271) expressed in E. Coli.
- Clone
- 5C7
- Isotype
- IgG1
- Top Product
- Discover our top product SPI1 Primary Antibody
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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PU.1 can regulate the ZNF300 promoter in APL-derived promyelocytes HL-60." in: Leukemia research, Vol. 34, Issue 12, pp. 1636-46, (2010) (PubMed).
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PU.1 can regulate the ZNF300 promoter in APL-derived promyelocytes HL-60." in: Leukemia research, Vol. 34, Issue 12, pp. 1636-46, (2010) (PubMed).
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- Target
- SPI1 (Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1))
- Alternative Name
- SPI1 (SPI1 Products)
- Background
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Description: This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.
Aliases: OF, PU.1, SFPI1, SPI-1, SPI-A
- Molecular Weight
- 42kDa
- Gene ID
- 6688
- HGNC
- 6688
- UniProt
- P17947
- Pathways
- Stem Cell Maintenance
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