The Mouse Monoclonal anti-ASS1 antibody has been validated for WB, ELISA and IHC. It is suitable to detect ASS1 in samples from Human, Mouse and Monkey. There is 1 publication available.
ASS1
Reactivity: Human
WB, IF
Host: Rabbit
Polyclonal
unconjugated
Application Notes
ELISA: 1/10000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified antibody in PBS with 0.05 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Laróvere, Angaroni, Antonozzi, Bezard, Shimohama, de Kremer: "Citrullinemia type I, classical variant. Identification of ASS-p~G390R (c.1168G>A) mutation in families of a limited geographic area of Argentina: a possible population cluster." in: Clinical biochemistry, Vol. 42, Issue 10-11, pp. 1166-8, (2009) (PubMed).
Target
ASS1
(Argininosuccinate Synthase 1 (ASS1))
Alternative Name
ASS1
Background
The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of ASS cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene.