COTL1 antibody
Quick Overview for COTL1 antibody (ABIN969510)
Target
See all COTL1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- COTL1 Antibody
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Purification
- Purified antibody
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Immunogen
- Purified recombinant fragment of human COTL1 expressed in E. Coli.
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Isotype
- IgG1
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Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Polymorphisms of COTL1 gene identified by proteomic approach and their association with autoimmune disorders." in: Experimental & molecular medicine, Vol. 41, Issue 5, pp. 354-61, (2009) (PubMed).
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: "Polymorphisms of COTL1 gene identified by proteomic approach and their association with autoimmune disorders." in: Experimental & molecular medicine, Vol. 41, Issue 5, pp. 354-61, (2009) (PubMed).
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- COTL1 (Coactosin-Like Protein)
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Alternative Name
- COTL1
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Background
- This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes.
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Molecular Weight
- 16 kDa
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UniProt
- Q14019
Target
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