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COTL1 antibody

This anti-COTL1 antibody is a Mouse Monoclonal antibody detecting COTL1 in ELISA and FACS. Suitable for Human. This Primary Antibody has been cited in 1 publication.
Catalog No. ABIN969510

Quick Overview for COTL1 antibody (ABIN969510)

Target

See all COTL1 Antibodies
COTL1 (Coactosin-Like Protein)

Reactivity

  • 47
  • 9
  • 5
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Host

  • 36
  • 9
  • 3
Mouse

Clonality

  • 40
  • 8
Monoclonal

Conjugate

  • 31
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
This COTL1 antibody is un-conjugated

Application

  • 38
  • 28
  • 27
  • 13
  • 7
  • 6
  • 6
  • 5
  • 3
  • 2
  • 1
  • 1
ELISA, Flow Cytometry (FACS)

Clone

5C8E3
  • Purpose

    COTL1 Antibody

    Purification

    Purified antibody

    Immunogen

    Purified recombinant fragment of human COTL1 expressed in E. Coli.

    Isotype

    IgG1
  • Application Notes

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified antibody in PBS with 0.05 % sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Jin, Shim, Kim, Chae, Chung: "Polymorphisms of COTL1 gene identified by proteomic approach and their association with autoimmune disorders." in: Experimental & molecular medicine, Vol. 41, Issue 5, pp. 354-61, (2009) (PubMed).

  • Target

    COTL1 (Coactosin-Like Protein)

    Alternative Name

    COTL1

    Background

    This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes.

    Molecular Weight

    16 kDa

    UniProt

    Q14019
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