anti-DFFA Antibodies

Protein Summary

Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Alternative names and synonyms associated with DFFA

• DNA fragmentation factor subunit alpha (DFFA) antibody
• DNA fragmentation factor, alpha subunit (Dffa) antibody
• DNA fragmentation factor, 45kDa, alpha polypeptide (dffa) antibody
• DNA fragmentation factor subunit alpha (Dffa) antibody
• DNA fragmentation factor, alpha polypeptide (dffa) antibody

• A330085O09Rik antibody
• DFF-45 antibody
• DFF1 antibody
• DFF35 antibody
• Dff45 antibody
• Show all synonym aliases
• DFFA antibody
• ICAD antibody
• ICAD-L antibody
• ICAD-S antibody
• zgc:92229 antibody

Protein level used designations for DFFA

DFF45 , DNA fragmentation factor 45 kDa subunit , DNA fragmentation factor subunit alpha , inhibitor of CAD , DFF-45 , DNA fragmentation factor, 45kDa, alpha polypeptide