ATPase, H+ Transporting, Lysosomal, V1 Subunit B, Member A (ATP6V1BA) Peptide
ATP6V1BA
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5510946
Quick Overview for ATPase, H+ Transporting, Lysosomal, V1 Subunit B, Member A (ATP6V1BA) Peptide (ABIN5510946)
Target
ATP6V1BA
(ATPase, H+ Transporting, Lysosomal, V1 Subunit B, Member A (ATP6V1BA))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-VATB1 antibody (Catalog #: ARP74408_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ATP6V1BA (ATPase, H+ Transporting, Lysosomal, V1 Subunit B, Member A (ATP6V1BA))
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Background
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This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found in the kidney. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness.
Alias Symbols: ATP6B1, VATB, VPP3
Protein Size: 513 -
Molecular Weight
- 56 kDa
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Gene ID
- 525
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NCBI Accession
- NP_001683
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UniProt
- P15313
Target
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