BAX Products
(BCL2-Associated X Protein (BAX))
Categories
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008].
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Featured BAX Categories
BAX Antibodies
High quality antibodies with extensive validation data.
BAX ELISA Kits
Reliable ELISA kits for a wide range of species.
BAX Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended BAX Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Chicken, Cow, Human, Mouse, Pig, Rabbit, Rat, Zebrafish (Danio rerio)
Application
ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p), IP, WB
Validations
- (34)
- (11)
Cat. No.
ABIN725390
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Avian, Cat, Chicken, Cow, Dog, Donkey, Goat, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Sheep
Application
IF, WB
Validations
- (7)
Cat. No.
ABIN6254209
Quantity
400 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, WB
Validations
- (7)
Cat. No.
ABIN7255864
Quantity
200 μL
Datasheet
Datasheet
Recommended BAX ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6963106
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6954058
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (4)
- (1)
Cat. No.
ABIN6954059
Quantity
96 tests
Datasheet
Datasheet
Recommended BAX Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (3)
- (1)
Cat. No.
ABIN1346446
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1346448
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3114412
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our BAX products
: "[8]-Gingerol exerts anti-myocardial ischemic effects in rats via modulation of the MAPK signaling pathway and L-type Ca2+ channels." in: Pharmacology research & perspectives, Vol. 9, Issue 5, pp. e00852, (2022) (PubMed).: "Astragaloside IV protects human cardiomyocytes from hypoxia/reoxygenation injury by regulating miR-101a." in: Molecular and cellular biochemistry, Vol. 470, Issue 1-2, pp. 41-51, (2021) (PubMed).
: "8-Gingerol Ameliorates Myocardial Fibrosis by Attenuating Reactive Oxygen Species, Apoptosis, and Autophagy via the PI3K/Akt/mTOR Signaling Pathway." in: Frontiers in pharmacology, Vol. 12, pp. 711701, (2021) (PubMed).
: "Synergistic Effects of Ginkgolide B and Protocatechuic Acid on the Treatment of Parkinson's Disease." in: Molecules (Basel, Switzerland), Vol. 25, Issue 17, (2021) (PubMed).
: "Exploration of the hepatoprotective effect and mechanism of magnesium isoglycyrrhizinate in mice with arsenic trioxide‑induced acute liver injury." in: Molecular medicine reports, Vol. 23, Issue 6, (2021) (PubMed).
: "Magnesium Isoglycyrrhizinate Alleviates Arsenic Trioxide-Induced Cardiotoxicity: Contribution of Nrf2 and TLR4/NF-κB Signaling Pathway." in: Drug design, development and therapy, Vol. 15, pp. 543-556, (2021) (PubMed).
: "Curcumin attenuates cytoplasmic/endoplasmic reticulum stress, apoptosis and cholinergic dysfunction in diabetic rat hippocampus." in: Metabolic brain disease, Vol. 35, Issue 4, pp. 637-647, (2020) (PubMed).
: "Involvement of redox status and the nuclear-related factor 2 in protecting against cadmium-induced renal injury with Sana Makki (Cassia senna L.) pre-treatment in male rats." in: Anais da Academia Brasileira de Ciências, Vol. 92, Issue 2, pp. e20191237, (2020) (PubMed).
: "Matrine inhibits the development and progression of ovarian cancer by repressing cancer associated phosphorylation signaling pathways." in: Cell death & disease, Vol. 10, Issue 10, pp. 770, (2020) (PubMed).
: "Zinc oxide nanoparticles induce murine photoreceptor cell death via mitochondria-related signaling pathway." in: Artificial cells, nanomedicine, and biotechnology, Vol. 46, Issue sup1, pp. 1102-1113, (2019) (PubMed).
Synonyms and alternative names related to BAX
BCL2 associated X, apoptosis regulator (BAX), BCL2-associated X protein L homeolog (bax.L), BCL2-associated X protein (bax), bcl2-associated X protein, a (baxa), BCL2-associated X protein (Bax), BCL2 associated X, apoptosis regulator (Bax), BAX, bax, bax-A, BAX-ALPHA, BCL2L4, fj16e01, wu:fc50b10, wu:fj16e01, xBax, xlbaxProtein level used designations for BAX
- BCL2-associated X protein
- BCL2-associated protein
- apoptosis regulator BAX
- bax zeta
- zBax1
- BCL2-associated X protein omega
- BCL2-associated X protein transcript variant delta2
- bcl-2-like protein 4
- bcl2-L-4
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