BCL6 Products
(B-Cell CLL/lymphoma 6 (BCL6))
Categories
The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2008].
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Featured BCL6 Categories
BCL6 Antibodies
High quality antibodies with extensive validation data.
BCL6 ELISA Kits
Reliable ELISA kits for a wide range of species.
BCL6 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended BCL6 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (2)
- (4)
Cat. No.
ABIN749843
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p)
Validations
- (5)
Cat. No.
ABIN3187827
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS, IHC, ICC, Neut
Validations
- (5)
Cat. No.
ABIN5611253
Quantity
0.1 mg
Datasheet
Datasheet
Recommended BCL6 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965111
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380950
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6951387
Quantity
96 tests
Datasheet
Datasheet
Recommended BCL6 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7121962
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346576
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3089985
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our BCL6 products
: "LncRNA AK023391 promotes tumorigenesis and invasion of gastric cancer through activation of the PI3K/Akt signaling pathway." in: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 194, (2018) (PubMed).: "Expansion of circulating follicular T helper cells associates with disease severity in childhood atopic dermatitis." in: Immunology letters, Vol. 189, pp. 101-108, (2017) (PubMed).
: "Increased levels of CCR7(lo)PD-1(hi) CXCR5+ CD4+ T cells, and associated factors Bcl-6, CXCR5, IL-21 and IL-6 contribute to repeated implantation failure." in: Experimental and therapeutic medicine, Vol. 14, Issue 6, pp. 5931-5941, (2017) (PubMed).
: "Cutting Edge: Distinct waves of BCL6 expression during T follicular helper cell development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 5, pp. 2089-92, (2011) (PubMed).
: "ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6." in: Immunity, Vol. 34, Issue 6, pp. 932-46, (2011) (PubMed).
: "Follicular helper CD4 T cells (TFH)." in: Annual review of immunology, Vol. 29, pp. 621-63, (2011) (PubMed).
: "Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation." in: Nature immunology, Vol. 11, Issue 2, pp. 114-20, (2010) (PubMed).
: "The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding." in: Nature immunology, Vol. 10, Issue 4, pp. 375-84, (2009) (PubMed).
: "Bcl6 mediates the development of T follicular helper cells." in: Science (New York, N.Y.), Vol. 325, Issue 5943, pp. 1001-5, (2009) (PubMed).
: "Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation." in: Science (New York, N.Y.), Vol. 325, Issue 5943, pp. 1006-10, (2009) (PubMed).
Synonyms and alternative names related to BCL6
B-cell CLL/lymphoma 6 L homeolog (bcl6.L), B-cell CLL/lymphoma 6 (bcl6), B-cell CLL/lymphoma 6 (BCL6), B cell leukemia/lymphoma 6 (Bcl6), B-cell CLL/lymphoma 6 (Bcl6), bcl5, Bcl5, BCL5, bcl6a, BCL6A, laz3, LAZ3, MGC132260, zbtb27, ZBTB27, znf51, ZNF51Protein level used designations for BCL6
- B-cell CLL/lymphoma 6
- B-cell CLL/lymphoma 6 (zinc finger protein 51)
- B-cell lymphoma 6 protein
- zinc finger protein 51
- B-cell leukemia/lymphoma 5
- B-cell leukemia/lymphoma 6
- B-cell lymphoma 6 protein homolog
- B-cell lymphoma 5 protein
- B-cell lymphoma 6 protein transcript
- BCL-5
- BCL-6
- cys-his2 zinc finger transcription factor
- lymphoma-associated zinc finger gene on chromosome 3
- protein LAZ-3
- zinc finger and BTB domain-containing protein 27
- zinc finger transcription factor BCL6S
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