BAX Protein (AA 1-192) (GST tag)
Quick Overview for BAX Protein (AA 1-192) (GST tag) (ABIN1346446)
Target
See all BAX ProteinsProtein Type
Origin
Source
Application
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Protein Characteristics
- AA 1-192
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Purification tag / Conjugate
- This BAX protein is labelled with GST tag.
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Purpose
- BAX (Human) Recombinant Protein (P01)
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Sequence
- MDGSGEQPRG GGPTSSEQIM KTGALLLQGF IQDRAGRMGG EAPELALDPV PQDASTKKLS ECLKRIGDEL DSNMELQRMI AAVDTDSPRE VFFRVAADMF SDGNFNWGRV VALFYFASKL VLKALCTKVP ELIRTIMGWT LDFLRERLLG WIQDQGGWDG LLSYFGTPTW QTATIFVAGV LTASLTIWKK MG
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Characteristics
- Human BAX full-length ORF ( AAH14175, 1 a.a. - 192 a.a.) recombinant protein with GST-tag at N-terminal.
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Purification
- in vitro wheat germ expression system
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue. -
Restrictions
- For Research Use only
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Buffer
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
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Handling Advice
- Aliquot to avoid repeated freezing and thawing.
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Storage
- -80 °C
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Storage Comment
- Best use within three months from the date of receipt of this protein.
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: "Bcl-w promotes cell invasion by blocking the invasion-suppressing action of Bax." in: Cellular signalling, Vol. 24, Issue 6, pp. 1163-72, (2012) (PubMed).
: "Viral apoptosis is induced by IRF-3-mediated activation of Bax." in: The EMBO journal, Vol. 29, Issue 10, pp. 1762-73, (2010) (PubMed).
: "Developmental shift of cyclophilin D contribution to hypoxic-ischemic brain injury." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 8, pp. 2588-96, (2009) (PubMed).
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: "Bcl-w promotes cell invasion by blocking the invasion-suppressing action of Bax." in: Cellular signalling, Vol. 24, Issue 6, pp. 1163-72, (2012) (PubMed).
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- BAX (BCL2-Associated X Protein (BAX))
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Alternative Name
- BAX
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Background
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Full Gene Name: BCL2-associated X protein
Synonyms: BCL2L4 -
Gene ID
- 581
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Pathways
- p53 Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
Target
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