anti-GRM2 Antibodies

Protein Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with GRM2

• glutamate metabotropic receptor 2 (GRM2) antibody
• glutamate receptor, metabotropic 2 (Grm2) antibody
• glutamate metabotropic receptor 2 (Grm2) antibody

• 4930441L02Rik antibody
• GLUR2 antibody
• Gprc1b antibody
• mGlu2 antibody
• mGluR2 antibody
• Show all synonym aliases
• mGluR7 antibody

Protein level used designations for GRM2

glutamate metabotropic receptor 2 , glutamate receptor homolog , metabotropic glutamate receptor 2 , G protein coupled receptor, family C, group 1, member B , G protein-coupled receptor, family C, group 1, member B , mGluR2