anti-Major Histocompatibility Complex, Class II, DM alpha Antibodies

Protein Summary

HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail.

Alternative names and synonyms associated with Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA)

• RT1 class II, locus DMa (RT1-DMa) antibody
• SLA-DM alpha chain (SLA-DMA) antibody
• major histocompatibility complex, class II, DM alpha (DLA-DMA) antibody
• histocompatibility 2, class II, locus DMa (H2-DMa) antibody
• major histocompatibility complex, class II, DM alpha (HLA-DMA) antibody

• D6S222E antibody
• DMA antibody
• H-2Ma antibody
• H2-Ma antibody
• HLA-DMA antibody
• Show all synonym aliases
• HLADM antibody
• RING6 antibody
• RT1.DMa antibody
• RT1.Ma antibody

Protein level used designations for HLA-DMA

RT1 class II, DM alpha , MHC class II-like alpha chain , major histocompatibility complex, class II, DM alpha , H2-M alpha , class II histocompatibility antigen, M alpha chain , histocompatibility 2, class II, locus Ma , HLA class II histocompatibility antigen, DM alpha chain , MHC class II antigen DMA , really interesting new gene 6 protein