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Browse our anti-Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) Antibodies

Full name:: anti-Major Histocompatibility Complex, Class II, DM alpha Antibodies (HLA-DMA)

On www.antibodies-online.com are 36 Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) Antibodies from 12 different suppliers available. Additionally we are shipping Major Histocompatibility Complex, Class II, DM alpha Kits (3) and Major Histocompatibility Complex, Class II, DM alpha Proteins (3) and many more products for this protein. A total of 46 Major Histocompatibility Complex, Class II, DM alpha products are currently listed.

Synonyms:: D6S222E, DMA, H-2Ma, H2-Ma, HLA-DMA, HLADM, RING6, RT1.DMa, RT1.Ma

list all antibodies	Gene Name	GeneID
	HLA-DMA	294274
	HLA-DMA	14998
	HLA-DMA	3108
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Most Popular Reactivities for anti-Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) Antibodies

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anti-Rat (Rattus) Antibodies:

4 WB Antibodies

anti-Mouse (Murine) Antibodies:

anti-Human Antibodies:

All available anti-Major Histocompatibility Complex, Class II, DM alpha Antibodies

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Relevant Pathways for anti-Major Histocompatibility Complex, Class II, DM alpha Antibodies

Cancer Immune Checkpoints

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Top referenced anti-Major Histocompatibility Complex, Class II, DM alpha Antibodies

Human Polyclonal HLA-DMA Primary Antibody for WB - ABIN6746965 : Nagamine, Kudoh, Kawasaki, Minoshima, Asakawa, Ito, Shimizu: Genomic organization and complete nucleotide sequence of the TMEM1 gene on human chromosome 21q22.3. in Biochemical and biophysical research communications 1997 (PubMed)
Show all 2 Pubmed References

More Antibodies against Major Histocompatibility Complex, Class II, DM alpha Interaction Partners

Human Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) interaction partners

The ARL15 and HLA-DMA gene polymorphisms are associated with RA risk in Northwestern Han Chinese population.
pH-susceptibility of HLA-DO tunes DO/DM ratios to regulate HLA-DM catalytic activity.
study therefore reveals that HLA-DM polymorphic residues have a considerable impact on HLA-DM catalytic activity.
The structure of the HLA-DM-HLA-DR complex shows major rearrangements of the HLA-DR peptide-binding groove.
DMA*01:01 (69.35%) and DMB*01:01 (52.5%) alleles were more frequent in Chinese Hans
Multiple mechanisms, operating along the biosynthetic pathway of class II molecules, contribute to DM-mediated increases in the abundance of low-CLIP-affinity alleles.
HLA DMA and DMB show no association with rheumatoid arthritis in US Caucasians.
The results suggest that HLA-DMA*0104 may represent a novel allele of susceptibility to systemic lupus erythematosus.
HLA-DMA may play an important role in pathogenesis of type 1 diabetes, and clinical status heterogeneity of type 1 diabetes may be related to genetic mechanism.
The absence of HLA-DR/DM interactions at the limiting membrane prevents local loading of MHC class II molecules in phagosomes
glycosylation promotes, but is not essential for, DMalphabeta ER exit; single DMalpha chains cannot fully oxidize without DMbeta, while DMbeta forms disulfide-linked homodimers without DMalpha

Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) Antigen Profile

Antigen Summary

HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail.

Alternative names and synonyms associated with Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA)

RT1 class II, locus DMa (RT1-DMa) antibody
SLA-DM alpha chain (SLA-DMA) antibody
major histocompatibility complex, class II, DM alpha (DLA-DMA) antibody
histocompatibility 2, class II, locus DMa (H2-DMa) antibody
major histocompatibility complex, class II, DM alpha (HLA-DMA) antibody

D6S222E antibody
DMA antibody
H-2Ma antibody
H2-Ma antibody
HLA-DMA antibody
HLADM antibody
RING6 antibody
RT1.DMa antibody
RT1.Ma antibody

Protein level used designations for HLA-DMA

RT1 class II, DM alpha , MHC class II-like alpha chain , major histocompatibility complex, class II, DM alpha , H2-M alpha , class II histocompatibility antigen, M alpha chain , histocompatibility 2, class II, locus Ma , HLA class II histocompatibility antigen, DM alpha chain , MHC class II antigen DMA , really interesting new gene 6 protein

GENE ID	SPECIES
294274	Rattus norvegicus
445528	Sus scrofa
481732	Canis lupus familiaris
14998	Mus musculus
3108	Homo sapiens

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Show all anti-Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) Antibodies with Pubmed References

Human Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) interaction partners

Antigen Summary

Alternative names and synonyms associated with Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA)

Protein level used designations for HLA-DMA