HLA-DMA antibody (AA 27-233) (Biotin)

Catalog No. ABIN7155577

Product Details anti-HLA-DMA Antibody (Biotin)

Target: HLA-DMA (Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA))

Binding Specificity: AA 27-233

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HLA-DMA antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human HLA class II histocompatibility antigen, DM alpha chain protein (27-233AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HLA-DMA

Target: HLA-DMA (Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA))

Alternative Name: HLA-DMA (HLA-DMA Products)

Synonyms: RT1.Ma antibody, RT1.DMa antibody, HLA-DMA antibody, H-2Ma antibody, H2-Ma antibody, D6S222E antibody, DMA antibody, HLADM antibody, RING6 antibody, RT1 class II, locus DMa antibody, SLA-DM alpha chain antibody, major histocompatibility complex, class II, DM alpha antibody, histocompatibility 2, class II, locus DMa antibody, RT1-DMa antibody, SLA-DMA antibody, DLA-DMA antibody, H2-DMa antibody, HLA-DMA antibody

Background:

Background: Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO.

Aliases: HLA-DMA antibody, DMA antibody, RING6HLA class II histocompatibility antigen antibody, DM alpha chain antibody, MHC class II antigen DMA antibody, Really interesting new gene 6 protein antibody

UniProt: P28067

Pathways: Cancer Immune Checkpoints