HLA-DMA antibody

Catalog No. ABIN7116015

The Rabbit Polyclonal anti-HLA-DMA antibody (ABIN7116015) specifically detects HLA-DMA in WB and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for HLA-DMA antibody (ABIN7116015)

Target: HLA-DMA (Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HLA-DMA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HLA-DMA Antibody

Purpose: HLA-DMA antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: major histocompatibility complex, class II, DM alpha

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for HLA-DMA

Target: HLA-DMA (Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA))

Alternative Name: HLA-DMA

Background:

Synonyms: HLA class II histocompatibility antigen, DM alpha chain|MHC class II antigen DMA|Really interesting new gene 6 protein|HLA-DMA|DMA|RING6

Background: Plays a critical role in catalyzing the release of class II-associated invariant chain peptide(CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO.

Molecular Weight: 55-60 kDa

Gene ID: 3108

UniProt: P28067

Pathways: Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response