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HLA-DMA Products

(Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA))

Categories

HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. [provided by RefSeq, Jul 2008].

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Featured HLA-DMA Categories

HLA-DMA Antibodies

High quality antibodies with extensive validation data.

HLA-DMA ELISA Kits

Reliable ELISA kits for a wide range of species.

HLA-DMA Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HLA-DMA Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IP
Validations
  • (6)
Cat. No. ABIN516471
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (4)
Cat. No. ABIN561267
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN2856977
Quantity 100 μL
Datasheet Datasheet

Recommended HLA-DMA ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN5591923
Quantity 96 tests
Datasheet Datasheet

Recommended HLA-DMA Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123830
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306743
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our HLA-DMA products

Nagamine, Kudoh, Kawasaki, Minoshima, Asakawa, Ito, Shimizu: "Genomic organization and complete nucleotide sequence of the TMEM1 gene on human chromosome 21q22.3." in: Biochemical and biophysical research communications, Vol. 235, Issue 1, pp. 185-90, (1997) (PubMed).

Scott, Chen, Rossier, Lalioti, Antonarakis: "Isolation of a human gene (HES1) with homology to an Escherichia coli and a zebrafish protein that maps to chromosome 21q22.3." in: Human genetics, Vol. 99, Issue 5, pp. 616-23, (1997) (PubMed).

Synonyms and alternative names related to HLA-DMA

RT1 class II, locus DMa (RT1-DMa), SLA-DM alpha chain (SLA-DMA), major histocompatibility complex, class II, DM alpha (DLA-DMA), histocompatibility 2, class II, locus DMa (H2-DMa), major histocompatibility complex, class II, DM alpha (HLA-DMA), D6S222E, DMA, H-2Ma, H2-Ma, HLA-DMA, HLADM, RING6, RT1.DMa, RT1.Ma

Protein level used designations for HLA-DMA

  • RT1 class II, DM alpha
  • MHC class II-like alpha chain
  • major histocompatibility complex, class II, DM alpha
  • H2-M alpha
  • class II histocompatibility antigen, M alpha chain
  • histocompatibility 2, class II, locus Ma
  • HLA class II histocompatibility antigen, DM alpha chain
  • MHC class II antigen DMA
  • really interesting new gene 6 protein
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