CCL2 Proteins
(Chemokine (C-C Motif) Ligand 2 (CCL2))
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. [provided by RefSeq, Jul 2008].
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Latest Publications for our CCL2 Proteins
: "Inflammatory Human Umbilical Cord-Derived Mesenchymal Stem Cells Promote Stem Cell-Like Characteristics of Cancer Cells in an IL-1β-Dependent Manner." in: BioMed research international, Vol. 2018, pp. 7096707, (2018) (PubMed).: "NADPH oxidase 1 plays a key role in diabetes mellitus-accelerated atherosclerosis." in: Circulation, Vol. 127, Issue 18, pp. 1888-902, (2013) (PubMed).
: "Dependence of monocyte chemoattractant protein 1 induced hyperalgesia on the isolectin B4-binding protein versican." in: Neuroscience, Vol. 159, Issue 2, pp. 780-6, (2009) (PubMed).
: "Role of oxidative stress in remodeling of the myocardial microcirculation in hypertension." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 26, Issue 8, pp. 1746-52, (2006) (PubMed).
: "Effect of acidosis on IL-8 and MCP-1 during hypoxia and reoxygenation in human NT2-N neurons." in: Brain research, Vol. 1113, Issue 1, pp. 64-73, (2006) (PubMed).
: "Leukocyte migration and activation by murine chemokines." in: Immunobiology, Vol. 195, Issue 4-5, pp. 499-521, (1997) (PubMed).
: "Chemokines." in: Blood, Vol. 90, Issue 3, pp. 909-28, (1997) (PubMed).
: "Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies." in: Journal of immunological methods, Vol. 188, Issue 1, pp. 117-28, (1996) (PubMed).
: "Biochemical and biologic characterization of murine monocyte chemoattractant protein-1. Identification of two functional domains." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 152, Issue 7, pp. 3541-9, (1994) (PubMed).
: "Serologic analysis of the mouse beta chemokine JE/monocyte chemoattractant protein-1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 153, Issue 8, pp. 3708-16, (1994) (PubMed).
Aliases for CCL2 Proteins
C-C motif chemokine ligand 2 (CCL2) Proteinschemokine (C-C motif) ligand 2 (Ccl2) Proteins
C-C motif chemokine ligand 2 (Ccl2) Proteins
chemokine (C-C motif) ligand 2 (CCL2) Proteins
C-C motif chemokine 2 (LOC101120093) Proteins
AI323594 Proteins
GDCF-2 Proteins
HC11 Proteins
HSMCR30 Proteins
JE Proteins
MCAF Proteins
MCP-1 Proteins
MCP-1A Proteins
MCP1 Proteins
MCP1A Proteins
SCYA2 Proteins
Scya2 Proteins
Sigje Proteins
SMC-CF Proteins
Did you look for something else?
- CCL19 Proteins
- CCL18 Proteins
- CCL17 Proteins
- CCL16 Proteins
- CCL15 Proteins
- CCL14 Proteins
- CCL13 Proteins
- Ccl12 Proteins
- CCL1 Proteins
- CCKBR Proteins
- CCKAR Proteins
- CCHCR1 Proteins
- CCDC98 Proteins
- CCDC93 Proteins
- CCDC91 Proteins
- CCDC90B Proteins
- CCDC89 Proteins
- CCDC88B Proteins
- CCDC86 Proteins
- CCDC85C Proteins
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