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anti-Human Claudin 1 Antibodies:
anti-Mouse (Murine) Claudin 1 Antibodies:
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Human Monoclonal Claudin 1 Primary Antibody for IHC (p), IP - ABIN563931
Mee, Grove, Harris, Hu, Balfe, McKeating: Effect of cell polarization on hepatitis C virus entry. in Journal of virology 2007
Show all 16 Pubmed References
Human Polyclonal Claudin 1 Primary Antibody for WB - ABIN2801934
Halford, Spencer, Greenwood, Winton, Hunt, Adamson: Assignment of claudin-1 (CLDN1) to human chromosome 3q28-->q29 with somatic cell hybrids. in Cytogenetics and cell genetics 2000
Show all 4 Pubmed References
Human Monoclonal Claudin 1 Primary Antibody for CyTOF, FACS - ABIN4898991
Farquhar, Hu, Harris, Davis, Brimacombe, Fletcher, Baumert, Rappoport, Balfe, McKeating: Hepatitis C virus induces CD81 and claudin-1 endocytosis. in Journal of virology 2012
Show all 3 Pubmed References
Human Polyclonal Claudin 1 Primary Antibody for ELISA, ICC - ABIN4298947
Dietze, Shihan, Stammler, Konrad, Scheiner-Bobis: Cardiotonic steroid ouabain stimulates expression of blood-testis barrier proteins claudin-1 and -11 and formation of tight junctions in Sertoli cells. in Molecular and cellular endocrinology 2015
Show all 2 Pubmed References
Human Polyclonal Claudin 1 Primary Antibody for IF (p), IHC (p) - ABIN686407
Wang, Chen, Liang, Yan, Lin, Liu, Luo, Huang, Li, Liu, Tang: Notch inhibition promotes fetal liver stem/progenitor cells differentiation into hepatocytes via the inhibition of HNF-1?. in Cell and tissue research 2014
Cow (Bovine) Polyclonal Claudin 1 Primary Antibody for IHC, WB - ABIN2778045
Coyne, Gambling, Boucher, Carson, Johnson: Role of claudin interactions in airway tight junctional permeability. in American journal of physiology. Lung cellular and molecular physiology 2003
Human Monoclonal Claudin 1 Primary Antibody for FACS - ABIN4895295
Giugliano, Petroff, Warren, Jasti, Linscheid, Ward, Kramer, Dobrinskikh, Sheiko, Gale, Golden-Mason, Winn, Rosen: Hepatitis C Virus Sensing by Human Trophoblasts Induces Innate Immune Responses and Recruitment of Maternal NK Cells: Potential Implications for Limiting Vertical Transmission. in Journal of immunology (Baltimore, Md. : 1950) 2015
the accumulation and toxicity of doxorubicin were rescued by CLDN1 siRNA in A549R cells. We suggest that CLDN1 is upregulated by CDDP resistance through activation of a PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies)/NF-kappaB (show NFKB1 Antibodies) pathway, resulting in the inhibition of penetration of anticancer drugs into the inner area of spheroids
Our data indicate that CLDN1 targeting with an anti-CLDN1 mAb results in decreased growth and survival of CRC (show CALR Antibodies) cells. This suggests that CLDN1 could be a new potential therapeutic target.
CLDN1 activates autophagy through up-regulation of ULK1 (show ULK1 Antibodies) phosphorylation and promotes drug resistance of non-small cell lung cancer cells to cisplatin.
Human Growth Hormone (show GH1 Antibodies) Inhibits CLAUDIN-1 (show CLDN7 Antibodies) Expression Through Activation of Signal Transducer and Activator of Transcription 3 (STAT3 (show STAT3 Antibodies)).
CLDN1 promotes invasion and metastasis in cervical cancer cells via the expression of EMT (show ITK Antibodies)/invasion-related genes.
Cycling hypoxia could induce significant changes in CLDN1 and CLDN7 (show CLDN7 Antibodies) expression in nasopharyngeal cancer cells, indirectly regulation P18 (show CDKN2C Antibodies) expression and affecting cell invasion/proliferation.
This study is the first to show a cytoplasmic function of claudin 1 (show CLDN7 Antibodies) as an autophagy regulator and provides the evidence that claudin 1 (show CLDN7 Antibodies)-mediated autophagy regulation is an integral part of the mechanism by which claudin 1 (show CLDN7 Antibodies) regulates cancer progression.
Rab25 (show RAB25 Antibodies) is amplified and enhances aggressiveness in luminal B cancers while in claudin-low tumors, Rab25 (show RAB25 Antibodies) is lost indicating possible anti-tumor functions
association of genetic polymorphisms of claudin-1 (show CLDN7 Antibodies) with small vessel vascular dementia
Glutamine (show GFPT1 Antibodies) increased claudin-1 (show CLDN7 Antibodies) expression in the colonic mucosa of patients with irritable bowel syndrome.
Taken together, these results demonstrate that BTZ (show CASC3 Antibodies)-induced claudin 1 expression may be a valuable therapeutic approach for AD.
Results suggest that TLR4 (show TLR4 Antibodies)-dependent claudin-1 internalization and secondary anion secretion contribute to irinotecan-induced diarrhea.
The data suggested that miR (show MLXIP Antibodies)-29a may regulate tumor growth and migration by targeting CLDN1.
Data show that the spatiotemporal expression of claudin-1 is dysregulated in homeobox (show PRRX1 Antibodies) (Msx) genes Msx1d/d/Msx2d/d uteri.
Cldn-1 is a positive regulator of osteoblast proliferation and differentiation.
We further demonstrate that KRT76 interacts with CLDN1 and propose that this interaction is necessary to correctly position CLDN1 in tight junctions.
MIR29 targets and reduces expression of CLDN1 and NKRF (show NKRF Antibodies) to increase intestinal permeability in inflammatory bowel disease.
Occludin (show OCLN Antibodies) and Claudin-1 expressions in the large intestine are under the circadian control, which is associated with temporal regulation of colonic permeability and also susceptibility to colitis.
regulates intestinal epithelial homeostasis via regulation of Notch (show NOTCH1 Antibodies)-signalling
Downregulation of Sirt1 (show SIRT1 Antibodies) and upregulation of the tight junction protein Claudin-1 by SIRT1 (show SIRT1 Antibodies)-mediated epigenetic regulation in podocytes contributed to albuminuria.
Tumor necrosis factor-alpha (show TNF Antibodies) increases claudin-1, 4, and 7 expression in renal tubular cells, altering permeability and transepithelial electrical resistance.
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.
, senescence-associated epithelial membrane protein 1
, claudin 19
, claudin 1
, tight junction protein