Claudin 1 antibody (AA 185-224)

Catalog No. ABIN7147875

Product Details anti-Claudin 1 Antibody

Target: Claudin 1 (CLDN1)

Binding Specificity: AA 185-224

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Claudin-10 protein (185-224AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Claudin 1

Target: Claudin 1 (CLDN1)

Alternative Name: CLDN1 (CLDN1 Products)

Synonyms: CLD1 antibody, ILVASC antibody, SEMP1 antibody, AI596271 antibody, cldn19 antibody, claudin-1 antibody, cld1 antibody, ilvasc antibody, semp1 antibody, CLDN1 antibody, claudin 1 antibody, claudin 1 S homeolog antibody, CLDN1 antibody, Cldn1 antibody, cldn1 antibody, cldn1.S antibody

Background:

Background: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. May form permselective paracellular pores, isoform 1 appears to create pores preferentially permeable to cations and isoform 2 for anions. Plays a key role in controlling cation selectivity and transport in the thick ascending limb (TAL) of Henle\\\'s loop in kidney.

Aliases: Claudin-10 antibody, Claudin10 antibody, CLD10_HUMAN antibody, CLDN 10 antibody, CLDN10 antibody, CLDN10 protein antibody, CPETRL 3 antibody, CPETRL3 antibody, HGNC:2033 antibody, OSP L antibody, OSP like protein antibody, OSP-like protein antibody, OSPL antibody

UniProt: P78369

Pathways: Cell-Cell Junction Organization, Hepatitis C