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anti-Human CX3CR1 Antibodies:
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Human Polyclonal CX3CR1 Primary Antibody for CyTOF, FACS - ABIN4900502
Fan, Xiong, Zhang, Yan, Jian, Xu, Zhao: MKEY, a Peptide Inhibitor of CXCL4-CCL5 Heterodimer Formation, Protects Against Stroke in Mice. in Journal of the American Heart Association 2016
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Mouse (Murine) Polyclonal CX3CR1 Primary Antibody for FACS - ABIN4897825
Wattananit, Tornero, Graubardt, Memanishvili, Monni, Tatarishvili, Miskinyte, Ge, Ahlenius, Lindvall, Schwartz, Kokaia: Monocyte-Derived Macrophages Contribute to Spontaneous Long-Term Functional Recovery after Stroke in Mice. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2016
Show all 3 Pubmed References
Human Polyclonal CX3CR1 Primary Antibody for ELISA, FACS - ABIN4301023
Aoyama, Inokuchi, Brenner, Seki: CX3CL1-CX3CR1 interaction prevents carbon tetrachloride-induced liver inflammation and fibrosis in mice. in Hepatology (Baltimore, Md.) 2010
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Human Polyclonal CX3CR1 Primary Antibody for FACS, IHC - ABIN110594
Held-Feindt, Hattermann, Mueerkoester, Wedderkopp, Knerlich-Lukoschus, Ungefroren, Mehdorn, Mentlein: CX3CR1 promotes recruitment of human glioma-infiltrating microglia/macrophages (GIMs). in Experimental cell research 2010
Human Monoclonal CX3CR1 Primary Antibody for ELISA, WB - ABIN560540
Nevo, Sagi-Assif, Meshel, Ben-Baruch, Jöhrer, Greil, Trejo, Kharenko, Feinmesser, Yron, Witz: The involvement of the fractalkine receptor in the transmigration of neuroblastoma cells through bone-marrow endothelial cells. in Cancer letters 2008
Human Polyclonal CX3CR1 Primary Antibody for FACS, WB - ABIN2473127
Imai, Hieshima, Haskell, Baba, Nagira, Nishimura, Kakizaki, Takagi, Nomiyama, Schall, Yoshie: Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion. in Cell 1997
Show all 2 Pubmed References
Mouse (Murine) Polyclonal CX3CR1 Primary Antibody for FACS - ABIN4897823
Nie, Li, Hu, Jin, Yu, Cai, Shao, Shen, Yi, Xiao, Shen, He: Atorvastatin improves plaque stability in ApoE-knockout mice by regulating chemokines and chemokine receptors. in PLoS ONE 2014
Human Monoclonal CX3CR1 Primary Antibody for FACS - ABIN4896932
Falk, Singh, Faber, Nissen, Hviid, Sørensen: CX3CL1/CX3CR1 and CCL2/CCR2 chemokine/chemokine receptor complex in patients with AMD. in PLoS ONE 2014
Mouse (Murine) Polyclonal CX3CR1 Primary Antibody for FACS - ABIN4897821
Arieta Kuksin, Gonzalez-Perez, Minter: CXCR4 expression on pathogenic T cells facilitates their bone marrow infiltration in a mouse model of aplastic anemia. in Blood 2015
CX3CR1 major allele carriers V249 and T280 are significantly associated with an increased total arterial blood volume of the whole brain, especially around the bilateral precuneus, left posterior cingulate cortex, and left posterior parietal cortex.
investigated the association of CX3CR1 839C/T, CX3CR1 745G/A, polymorphisms with Age-Related Macular Degeneration (AMD (show AMD1 Antibodies)) risk. These associated with an increased AMD (show AMD1 Antibodies) risk (CX3CR1 839C/T, additive model: aOR=2.682, 95% CI=1.119-5.709, P=0.022, recessive model: aOR=2.729, 95% CI=1.141-6.048, P=0.010; CX3CR1 745G/A, additive model: aOR=2.614, 95% CI=1.231-6.012, P=0.020, recessive model: aOR=2.340, 95% CI=1.227-5.993, P=0.011
CX3CR1 regulated chondrocyte proliferation.
We detected a statistically significant association between the variant Ala55Thr in CX3CR1 with schizophrenia and autism spectrum disorder phenotypes
This study shown that CX3CR1 expression in both Microglia and Astrocytes in hippocampus in affected by stroke, Alzheimer's disease, and Lewy body dementia.
The US28 gene product has maintained the function of the ancestral gene and has the ability to bind and signal in response to human CX3CL1 (show CX3CL1 Antibodies), the natural ligand for CX3CR1.
Our findings demonstrate that motility, invasion, and contact-independent growth of PDAC cells all increase following CX3CL1 (show CX3CL1 Antibodies) exposure, and that antagonism of CX3CR1 by the inhibitor JMS (show ATRX Antibodies)-17-2 reduces each of these phenotypes and correlates with a downregulation of AKT (show AKT1 Antibodies) phosphorylation.
in Crohn's disease patients, a missense mutation in the gene encoding CX3CR1 was identified and found to be associated with impaired antifungal responses
CX3CL1 (show CX3CL1 Antibodies)/CX3CR1 axis plays a key role in the development of ischemia-induced oligodendrocyte injury via p38MAPK (show MAPK14 Antibodies) signaling pathway.
Soluble FKN that was efficiently shed from the surface of LPS (show IRF6 Antibodies)-activated ECs in response to binding of CD16 (show CD16 Antibodies)(+) monocytes to ECs, diminished monocyte adhesion in down-regulating CX3CR1 expression on the surface of CD16 (show CD16 Antibodies)(+) monocytes resulting in decreased TNF (show TNF Antibodies)-secretion.
CXCR1 (show CXCR1 Antibodies) mediates neuronal apoptotic cell death in ischemia.
These data implicate sex differences in microglial activation in the modulation of energy homeostasis and identify CX3CR1 signalling as a potential therapeutic target for the treatment of obesity.
Using the Theiler's virus model of encephalitis in C57BL/6 mice study shows that CCR2 (show CCR2 Antibodies) as well as CX3CR1 plays a key role in the accumulation of myeloid cells in the CNS and activation of hippocampal myeloid cells upon infection.
Ang II (show AGT Antibodies) up-regulates CX3CR1 expression in VSMCs via NADPH oxidase (show NOX1 Antibodies)/ROS (show ROS1 Antibodies)/p38 MAPK (show MAPK14 Antibodies) pathway and the CX3CL1 (show CX3CL1 Antibodies)/CX3CR1 axis contributes to the proliferative and pro-inflammatory effects of Ang II (show AGT Antibodies) in VSMCs.
CX3CR1 ablation enhanced the neurotrophic action of microglia in Mecp2KO mice
These findings indicate that emotional and cognitive stress resilience involves CX3CR1-dependent basal and stress-induced alterations in hippocampal transcription
The effect of CX3CR1 deletion on murine acetabular development provides suggestive evidence of a susceptibility inducing role of the CX3CR1 gene on developmental dysplasia of the hip.
In Cx3cr1(-/-) mice, adult-born-granule-cells exhibited reduced spine density, dynamics and size, concomitantly with reduced contacts between Cx3cr1-deficient microglia and adult-born-granule-cells' dendritic shafts, along with increased proportion of microglia-contacted spines.
reveal CX3CR1 as a novel target for the clearance of extracellular Tau
These findings suggest that fractalkine receptor is not a universal regulator of synaptic plasticity, but rather has heterogeneous roles in specific brain regions and life stages.
Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene.
, CX3C chemokine receptor 1
, G protein-coupled receptor 13
, G-protein coupled receptor 13
, beta chemokine receptor-like 1
, chemokine (C-C) receptor-like 1
, chemokine (C-X3-C) receptor 1
, fractalkine receptor
, CX3C chemokine receptor 1-like
, Fractalkine receptor
, chemokine receptor 1
, chemokine (C-X3-C motif) receptor 1