Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species and application
anti-Human FABP1 Antibodies:
anti-Mouse (Murine) FABP1 Antibodies:
anti-Rat (Rattus) FABP1 Antibodies:
Go to our pre-filtered search.
Human Polyclonal FABP1 Primary Antibody for ICC, IF - ABIN4309903
Yan, Janda, Chang, Zheng, Larkin, Luca, Chia, Mah, Han, Terry, Ootani, Roelf, Lee, Yuan, Li, Bolen, Wilhelmy, Davies, Ueno, von Furstenberg, Belgrader, Ziraldo, Ordonez, Henning, Wong, Snyder et al.: Non-equivalence of Wnt and R-spondin ligands during Lgr5(+) intestinal stem-cell self-renewal. ... in Nature 2017
Show all 2 Pubmed References
Human Monoclonal FABP1 Primary Antibody for IA, FACS - ABIN2191917
Bax, Siersema, Haringsma, Kuipers, Vos, Van Dekken, Van Vliet, Kusters: High-grade dysplasia in Barrett's esophagus is associated with increased expression of calgranulin A and B. in Scandinavian journal of gastroenterology 2007
urine L-FABP/C is permanently elevated in chronic kidney disease patients.
Our data suggests that the polymorphism in genes IL-1beta (show IL1B Antibodies), IL-1Ra (show IL1RN Antibodies) and FABP1 included in this study are not associated with PCOS development, but can influence important biochemical and metabolic parameters in PCOS.
On PICU day 1, interleukin-18 (show IL18 Antibodies) predicted acute kidney injury with area under the curve=0.82, but neutrophil gelatinase-associated lipocalin (show LCN2 Antibodies) and liver fatty acid binding protein predicted acute kidney injury with area under the curve of less than or equal to 0.69; on PICU day 2, area under the curve was higher. Interleukin-18 (show IL18 Antibodies) and liver fatty acid binding protein on day 1 predicted prolonged acute kidney injury.
In total, 68 miRNAs potentially targeting FABP1 were selected; of these, miR (show MLXIP Antibodies)-3941, miR (show MLXIP Antibodies)-4517, and miR (show MLXIP Antibodies)-4672 directly targeted the FABP1 3' untranslated region. Mimics of the three miRNAs substantially repressed FABP1 expression at translational level and led to HepG2 cell resistance to steatosis and cell injury induced by free fatty acids mixture, which rescue of FABP1 overexpression reversed.
This study demonstrated that the loss of FABP1 expression is associated with MSI (show MSI1 Antibodies) carcinomas and that interferon gamma (show IFNG Antibodies) stimulation plays a role in this process via its interaction with PPARgamma (show PPARG Antibodies).
Hepatic adenomas co-occurring with fibrolamellar carcinomas show LFABP loss and are negative for PRKACA (show PRKACA Antibodies) rearrangements, indicating they are genetically distinct lesions. These data also demonstrate that LFABP loss, which characterizes HNF1-alpha (show HNF1A Antibodies) inactivation, is a consistent feature of fibrolamellar carcinoma, indicating HNF1-alpha (show HNF1A Antibodies) inactivation is an important event in fibrolamellar carcinoma pathogenesis.
studies indicate that FABP1 is essential for proper lipid metabolism in differentiated enterocytes, particularly concerning fatty acids uptake and its basolateral secretion.
CDH5 (show CDH5 Antibodies) and FABP1 expression levels were both elevated in drug-induced liver injury.
A high resolution NMR comparative molecular analysis of L-FABP T94T and L-FABP T94A in their unbound states and in the presence of representative ligands of the fatty acid and bile acid classes showed that threonine to alanine replacement did not result in strongly perturbed structural and dynamic features, although differences in oleic acid binding by the two variants were detected.
Studies show that despite overall tertiary structure similarity, the hFABP1 differs significantly from rat FABP1 in secondary structure, much larger ligand binding cavity, and affinities/specificities for some ligands. Moreover, while both mouse and hFABP1 mediate ligand induction of PPARA (show PPARA Antibodies), they differ markedly in genes induced. hFABP1 T94A variant is associated with altered body mass index.[review]
Ablating both Fabp1 and Scp2/Scpx (show SCP2 Antibodies) (TKO (show MRPS12 Antibodies)) induces hepatic phospholipid and cholesterol accumulation in high fat-fed mice
role of Fabp1/Scp-2 (show CRISP3 Antibodies) in hepatic phytol metabolism
Individually ablating SCPx (show SCP2 Antibodies) or SCP2/SCPx (show SCP2 Antibodies) elicited concomitant upregulation of L-FABP.
Lack of a significant decrease in the flux of HDL-[(3)H]CE to biliary FC or bile acids in FABP1(-/-) mice indicates the likely compensation of its function by an as yet unidentified mechanism. Taken together, these studies demonstrate that FABP1 and SCP2 facilitate the preferential movement of HDL-CEs to bile for final elimination
data showed that Fabp1 gene ablation markedly diminished the impact of high-fat diet on brain endocannabinoid levels, especially in male mice
Studies show that despite overall tertiary structure similarity, the hFABP1 differs significantly from rat FABP1 in secondary structure, much larger ligand binding cavity, and affinities/specificities for some ligands. Moreover, while both mouse and hFABP1 mediate ligand induction of PPARA (show PPARA Antibodies), they differ markedly in genes induced.
FABP1 knockout increased brain levels of arachidonic acid-containing endocannabinoids
L-FABP was more important in hepatic retention of bile acids, while SCP-2/SCP-x (show SCP2 Antibodies) more broadly affected biliary bile acid and phospholipid levels.
These findings suggest that some of the phenotypic divergence between the two L-Fabp(-/-) lines may reflect unanticipated differences in genetic background, underscoring the importance of genetic background in phenotypic characterization.
Loss of L-FABP and SCP-2 (show CRISP3 Antibodies), or both induces hepatic lipid accumulation in female mice and mimics non-alcoholic fatty liver disease.
combinatorial interactions between multiple regulatory factors are responsible for the gene expression of L-FABP in the liver
This gene encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. This protein and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism.
fatty acid-binding protein 1
, fatty acid-binding protein, liver
, liver-type fatty acid-binding protein
, 14 kDa selenium-binding protein
, fatty acid binding protein liver
, squalene- and sterol-carrier protein
, fatty acid binding protein 1, liver
, fafatty acid binding protein 1, liver
, fatty acid-binding protein
, liver fatty acid binding protein
, fatty acid binding protein 1-A, liver
, LOW QUALITY PROTEIN: fatty acid-binding protein, liver