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Full name:: Structure Specific Recognition Protein 1 Proteins (SSRP1)

On www.antibodies-online.com are 7 Structure Specific Recognition Protein 1 (SSRP1) Proteins from 5 different suppliers available. Additionally we are shipping Structure Specific Recognition Protein 1 Antibodies (113) and Structure Specific Recognition Protein 1 Kits (30) and many more products for this protein. A total of 155 Structure Specific Recognition Protein 1 products are currently listed.

Synonyms:: ATHMG, C81323, Cf5, CG4817, CIIDBP, DDBDRAFT_0188842, DDBDRAFT_0216434, DDB_0188842, DDB_0216434, Dmel\\CG4817, dSsrp, dSSRP1, FACT, FACT80, high mobility group, Hmg1-rs1, Hmgi-rs3, Hmgox, NFD, NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR D, ssrp, Ssrp1, T160, wu:fa11b03, wu:fd10f06

list all proteins	Gene Name	GeneID	UniProt
	SSRP1	6749	Q08945
	SSRP1	20833	Q08943
	SSRP1	81785	Q04931
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Structure Specific Recognition Protein 1 Proteins (SSRP1) by Origin

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Relevant Pathways for Structure Specific Recognition Protein 1 Proteins

Chromatin Binding

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Arabidopsis thaliana Structure Specific Recognition Protein 1 (SSRP1) interaction partners

FACT (SSRP1 and SPT16 (show SUPT16 Proteins)) is a novel factor required for the accumulation of anthocyanins in response to light-induction.
Active DNA demethylation by DEMETER requires SSRP1 function through a distinctly different process from direct DNA methylation (show HELLS Proteins) control.
SPT16 and SSRP1 are critically involved in the regulation of leaf growth, flowering time and seed production, and interact with HUB1/2.

Fruit Fly (Drosophila melanogaster) Structure Specific Recognition Protein 1 (SSRP1) interaction partners

results show that FACT, a heterodimer of dSPT16 (show SUPT16H Proteins) and dSSRP1, associates with GAGA factor through its dSSRP1 subunit & facilitates chromatin remodeling; interactions between GAGA factor and spt16 (show SUPT16H Proteins) implicate the GAGA factor-FACT complex in Hox (show MSH2 Proteins) gene expression
Results report the solution structure of the HMG (show HMGCR Proteins)-box domain in Drosophila SSRP1.
rapid chromatin transactions during early embryogenesis through the dephosphorylation of some sites in the maternally transmitted dSSRP1

Zebrafish Structure Specific Recognition Protein 1 (SSRP1) interaction partners

Ssrp1a is essential for proliferation and differentiation during eye and liver organogenesis.

Human Structure Specific Recognition Protein 1 (SSRP1) interaction partners

Data revealed that SSRP1 is highly overexpressed in glioma tissues at both the mRNA and protein levels and correlated with tumor grade. Further analysis demonstrated that that SSRP1 regulates the proliferation and metastasis of glioma cells via the MAPK (show MAPK1 Proteins) signaling pathway.
These data uncover a previously unknown role for SSRP1 in promoting the activation of the Wnt (show WNT2 Proteins) signaling pathway activity during cellular differentiation.
The association of LEDGF (show PSIP1 Proteins) proteins with the FACT complex and give further support to a role of SSRP1 in HIV-1 infection.
Results show that SSRP1 upregulation contributed to hepatocellular carcinoma development and the tumor-suppressive miR (show MLXIP Proteins)-497 served as its negative regulator.
FACT chaperone stabilizes the soluble CENP-T (show CENPT Proteins)/-W complex in the cell and promotes dynamics of exchange, enabling CENP-T (show CENPT Proteins)/-W deposition at centromeres.
SSRP1/Ets-1 (show ETS1 Proteins)/Pim-3 (show PIM3 Proteins) signalling is tightly associated with the proliferation, apoptosis, autophagy, invasion and clonogenicity of nasopharyngeal carcinoma cells, and blockage of this signalling facilitates chemosensitivity of the cells to docetaxel.
Our studies facilitate the understanding of SSRP1 and provide insights into the molecular mechanisms of interaction with DNA and histones of the FACT complex.
AID accesses the H2B N-terminal basic region exposed by partial unwrapping of the nucleosomal DNA, thereby triggering the invasion of FACT into the nucleosome
FACT is required for TOP1 (show TOP1 Proteins) binding to H3K4me3 at non-B DNA containing chromatin for the site-specific cleavage.
FACT, NF-kappaB (show NFKB1 Proteins), and cell-cycle progression are inhibited by quinacrine, which overcomes resistance to erlotinib in non-small cell lung cancer

Mouse (Murine) Structure Specific Recognition Protein 1 (SSRP1) interaction partners

FACT is required for TOP1 (show TOP1 Proteins) binding to H3K4me3 at non-B DNA containing chromatin for the site-specific cleavage.
Ssrp1 appears to encode nonredundant and p53 (show TP53 Proteins)-independent functions that are essential for cell viability

Structure Specific Recognition Protein 1 (SSRP1) Protein Profile

Protein Summary

The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.

Alternative names and synonyms associated with Structure Specific Recognition Protein 1 (SSRP1)

high mobility group (HMG)
FACT complex subunit Ssrp1 (CpipJ_CPIJ002953)
FACT complex subunit Ssrp1 (CpipJ_CPIJ020011)
FACT complex subunit SSRP1 (CMU_019430)
FACT complex subunit Ssrp1 (Tsp_07406)
FACT complex subunit SSRP1 (LOC100286423)
Structure specific recognition protein (Ssrp)
structure specific recognition protein 1 (ssrp1)
structure specific recognition protein 1 (SSRP1)
transcription factor protein (ssrp1)
FACT complex subunit SSRP1 (ssrp1)
structure specific recognition protein 1a (ssrp1a)
SSRP1 protein (nfd110)
structure specific recognition protein 1 S homeolog (ssrp1.S)
structure specific recognition protein 1 (Ssrp1)

ATHMG protein
C81323 protein
Cf5 protein
CG4817 protein
CIIDBP protein
DDBDRAFT_0188842 protein
DDBDRAFT_0216434 protein
DDB_0188842 protein
DDB_0216434 protein
Dmel\\CG4817 protein
dSsrp protein
dSSRP1 protein
FACT protein
FACT80 protein
high mobility group protein
Hmg1-rs1 protein
Hmgi-rs3 protein
Hmgox protein
NFD protein
NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR D protein
ssrp protein
Ssrp1 protein
T160 protein
wu:fa11b03 protein
wu:fd10f06 protein

Protein level used designations for SSRP1

, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , FACT complex subunit Ssrp1 FACT complex subunit SSRP1 CG4817-PA Ssrp-PA chorion factor structure specific recognition protein structure-specific recognition protein Ssrp1 protein structure specific recognition protein 1 structure-specific recognition protein 1 facilitates chromatin transcription complex subunit SSRP1 FACT complex subunit SSRP1-like CL1186_1 CL1186_1_ov mcg6102 nfd114 recombination signal sequence recognition protein 1 zm-SSRP1 FACT 80 kDa subunit FACTp80 chromatin-specific transcription elongation factor 80 kDa subunit cisplatin-DNA SSRP facilitates chromatin remodeling 80 kDa subunit facilitates chromatin transcription complex 80 kDa subunit hSSRP1 high mobility group box DNA unwinding factor 87 kDa subunit DUF87 facilitates chromatin transcription complex subunit ssrp1 T160 delta-crystallin enhancer binding protein high mobility group 1 protein Structure-specific recognition protein 1

GENE ID	SPECIES
822505	Arabidopsis thaliana
6034218	Culex quinquefasciatus
6054785	Culex quinquefasciatus
6995379	Cryptosporidium muris RN66
10898616	Trichinella spiralis
100286423	Salmo salar
37767	Drosophila melanogaster
447983	Xenopus (Silurana) tropicalis
451188	Pan troglodytes
706614	Macaca mulatta
778769	Ciona intestinalis
7448150	Thalassiosira pseudonana CCMP1335
8627610	Dictyostelium discoideum AX4
100025230	Monodelphis domestica
100066933	Equus caballus
100413716	Callithrix jacchus
100433805	Pongo abelii
100476319	Ailuropoda melanoleuca
100607407	Nomascus leucogenys
386844	Danio rerio
542007	Zea mays
6749	Homo sapiens
399344	Xenopus laevis
396509	Gallus gallus
282082	Bos taurus
20833	Mus musculus
81785	Rattus norvegicus
100357630	Oryctolagus cuniculus
100723239	Cavia porcellus
100624907	Sus scrofa
475970	Canis lupus familiaris
101104524	Ovis aries

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