SSRP1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2732708

Product Details

Target: SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This SSRP1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human SSRP1 / FACT80 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))

Alternative Name: Ssrp1,fact80 (SSRP1 Products)

Synonyms: ATHMG Protein, NFD Protein, NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR D Protein, SSRP1 Protein, high mobility group Protein, ssrp1 Protein, CG4817 Protein, Cf5 Protein, Dmel\\CG4817 Protein, DssRP Protein, SSRP Protein, dSSRP Protein, dSSRP1 Protein, dSsrp Protein, ssrp Protein, Ssrp1 Protein, DDBDRAFT_0188842 Protein, DDBDRAFT_0216434 Protein, DDB_0188842 Protein, DDB_0216434 Protein, wu:fa11b03 Protein, wu:fd10f06 Protein, FACT Protein, FACT80 Protein, T160 Protein, CIIDBP Protein, C81323 Protein, Hmg1-rs1 Protein, Hmgi-rs3 Protein, Hmgox Protein, high mobility group Protein, FACT complex subunit Ssrp1 Protein, FACT complex subunit SSRP1 Protein, Structure specific recognition protein Protein, structure specific recognition protein 1 Protein, transcription factor protein Protein, structure specific recognition protein 1a Protein, SSRP1 protein Protein, structure specific recognition protein 1 S homeolog Protein, HMG Protein, CpipJ_CPIJ002953 Protein, CpipJ_CPIJ020011 Protein, CMU_019430 Protein, Tsp_07406 Protein, LOC100286423 Protein, Ssrp Protein, ssrp1 Protein, SSRP1 Protein, ssrp1a Protein, nfd110 Protein, ssrp1.S Protein, Ssrp1 Protein

Background: The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.

Molecular Weight: 80.9 kDa

NCBI Accession: NP_003137

Pathways: Chromatin Binding