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Equine herpesvirus type 1 infection significantly decreased the expression of integrin alpha 6 in nasal mucosa epithelial cells.
Integrin alpha 6 Expression on Microglia Surface and Motility on Laminin Is Up-regulated upon Adenosine Diphosphate Stimulation.
Ahr (show AHR ELISA Kits) ligand aminoflavone targets breast cancer cells with stem cell-like properties, at least in part by abolishing alpha6-integrin expression.
interaction of alpha6beta1 in embryonic stem cells (ECCs) with laminin-1 (show LAMA1 ELISA Kits) activates alpha6beta1/CD151 (show CD151 ELISA Kits) signaling which programs ESCs (show NR2E3 ELISA Kits) toward the endothelial cells lineage fate
Exome sequencing analysis between SM/J and A/J mice identified 4 genes (Itga6, Zak (show ZAK ELISA Kits), Gpr155, and Mtx2 (show MTX2 ELISA Kits)) with nonsynonymous coding SNPs. These four genes might be candidate genes for type 2 diabetes caused by gene-gene interactions.
Immunohistological analysis of the tumors showed that Tie2 (show TEK ELISA Kits)-dependent a6 gene deletion was associated with reduced tumor vascularization and with reduced infiltration of proangiogenic Tie2 (show TEK ELISA Kits)-expressing macrophages
CD29 (show ITGB1 ELISA Kits) and CD49f have a critical role of in mediating cancer metastasis.
NLGN1 (show NLGN1 ELISA Kits) and alpha6 integrin preferentially colocalize in the mature retinal vessels, whereas NLGN1 (show NLGN1 ELISA Kits) deletion causes an aberrant VE-cadherin (show CDH5 ELISA Kits), laminin and alpha6 integrin distribution in vessels
alpha6 integrin is an essential upstream regulator of the IGF-1R (show IGF1R ELISA Kits) survival pathway that regulates the activity level of caspase-3 (show CASP3 ELISA Kits) for it to signal differentiation initiation of lens epithelial cells.
Deficiency of integrin alpha(6)beta(4) is modestly but significantly suppressed reporter-gene transduction by papillomaviruses in conditional integrin beta(4 (show ITGB4 ELISA Kits)) knockout mice.
The alpha6beta1 integrin is a netrin-4 (show NTN4 ELISA Kits) receptor in endothelial cells.
IGF2 also requires integrin binding for signaling functions, and the IGF2 mutants that cannot bind to integrins act as antagonists of IGF1R (show IGF1R ELISA Kits).
By directly binding to the 3'UTRs of ITGA6 and ITGB1 (show ITGB1 ELISA Kits), we found miR (show MLXIP ELISA Kits)-30e-5p to suppress mainly the adhesion of ITGA6 in CRC (show CALR ELISA Kits) cells to laminin.Taken together, miR (show MLXIP ELISA Kits)-30e-5p is a novel effector of P53 (show TP53 ELISA Kits)-induced suppression of migration, invasion and metastasis
The SALL4 (show SALL4 ELISA Kits) - integrin alpha6 - integrin beta1 network promotes cell migration for metastasis via activation of focal adhesion dynamics in basal-like breast cancer cells.
FACS analysis of primary human Benign Prostatic Hyperplasia tissues confirms expansion of CD49f basal epithelia in patients with Basal cell hyperplasia.
alpha6(high)/CD71 (show TFRC ELISA Kits)(low) cells give rise to a thicker pluristratified epithelium with lower seeding density and display a low Ki67 (show MKI67 ELISA Kits) positive cells number, showing that they have reached the balance between proliferation and differentiation.
The A380T Single Nucleotide Polymorphism of the ITGA6 gene was not associated with breast cancer development in the analyzed population of Misiones, Argentina.
Positive Thy1 (show THY1 ELISA Kits) and CD49f expression is significantly associated with the progression and poor prognosis of chondrosarcoma.
Platelet-enhanced endothelial colony forming cell angiogenesis requires platelet tetraspanin CD151 (show CD151 ELISA Kits) and alpha6beta1 integrin signaling.
these findings identify CD151 (show CD151 ELISA Kits) and its interactions with integrins a3 and a6 as potential therapeutic targets for inhibiting stemness-driving mechanisms and stem cell populations in Glioblastoma.
formation of CD151 (show CD151 ELISA Kits)-integrin complex was likely to be a prerequisite for CD151 (show CD151 ELISA Kits)-induced angiogenesis and signaling pathways
The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Two transcript variants encoding different isoforms have been found for this gene.
CD49 antigen-like family member F
, integrin alpha-6
, integrin alpha6B
, integrin, alpha 6
, integrin alpha 6
, integrin alpha 6 subunit
, integrin alpha chain, alpha 6
, integrin alpha-6-like