DEFA1/DEFA3 antibody
Quick Overview for DEFA1/DEFA3 antibody (ABIN7190457)
Target
Reactivity
Host
Clonality
Application
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Cross-Reactivity
- Human
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Purification
- Antigen affinity purification
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Immunogen
- Synthetic peptide of Human DEFA1/3
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Isotype
- IgG
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Application Notes
- ELISA:1:1000-1:2000, IHC:1:25-1:100,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- DEFA1/DEFA3 (DEFA1A3) (Defensin, alpha 1 and alpha 3, Variable Copy Number Locus (DEFA1A3))
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Alternative Name
- DEFA1/DEFA3
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Background
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Background: Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Defensin, alpha Several alpha 3, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8.
Aliases: defensin, alpha 1/3
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UniProt
- P59665, P59666
Target
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