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anti-Human ERCC2 Antibodies:
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Human Polyclonal ERCC2 Primary Antibody for IHC - ABIN966088
Weber, Salazar, Stewart, Thompson: ERCC2: cDNA cloning and molecular characterization of a human nucleotide excision repair gene with high homology to yeast RAD3. in The EMBO journal 1990
Show all 9 Pubmed References
The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
, DNA excision repair protein ERCC-2
, DNA repair protein complementing XP-D cells
, TFIIH 80 kDa subunit
, TFIIH basal transcription factor complex 80 kDa subunit
, TFIIH basal transcription factor complex helicase XPD subunit
, TFIIH basal transcription factor complex helicase subunit
, TFIIH p80
, basic transcription factor 2 80 kDa subunit
, xeroderma pigmentosum complementary group D
, xeroderma pigmentosum group D-complementing protein
, excision repair cross-complementing rodent repair deficiency, complementation group 2 (xeroderma pigmentosum D)
, excision repair cross-complementing rodent repair deficiency, complementation group 2 protein
, excision repair cross-complementing rodent repair deficiency, complementation group 2
, excision repair cross-complementing 2
, DNA-repair protein complementing XP-D cells
, excision repair cross-complementing rodent repair deficiency, complementation group 6-like group 2
, lethal (2) SH2137
, xeroderma pigmentosum D