MCM4 Proteins
6 Minichromosome Maintenance Deficient 4 (MCM4) Proteins from 3 manufacturers are available on www.antibodies-online.com.
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Minichromosome Maintenance Deficient 4 (MCM4) (AA 1-863) protein (GST tag) Protein
Minichromosome Maintenance Deficient 4 (MCM4) (AA 2-863) protein (His tag) Protein
Minichromosome Maintenance Deficient 4 (MCM4) (AA 2-862) protein (His tag) Protein
Minichromosome Maintenance Deficient 4 (MCM4) (AA 267-366) protein (GST tag) Protein
Minichromosome Maintenance Deficient 4 (MCM4) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag) Protein
Minichromosome Maintenance Deficient 4 (MCM4) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag) Protein
MCM4 Protein Profile
Protein Summary
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported.
Alternative names and synonyms associated with MCM4
- minichromosome maintenance complex component 4 (mcm4) antibody
- minichromosome maintenance complex component 4 (MCM4) antibody
- minichromosome maintenance complex component 4 (Mcm4) antibody
- 19G antibody
- AI325074 antibody
- AU045576 antibody
- cb1025 antibody
- Cdc21 antibody
- CDC54 antibody
- fc12c09 antibody
- fj85g09 antibody
- hCdc21 antibody
- hm:zeh1616 antibody
- mcdc21 antibody
- Mcmd4 antibody
- mKIAA4003 antibody
- NKCD antibody
- NKGCD antibody
- P1-CDC21 antibody
- wu:fc12c09 antibody
- wu:fj85g09 antibody
- zeh1616 antibody
Protein level used designations for MCM4
DNA replication licensing factor mcm4 , MCM4 minichromosome maintenance deficient 4 , minichromosome maintenance protein 4 , DNA replication licensing factor MCM4 , CDC21 homolog , homolog of S. pombe cell devision cycle 21 , minichromosome maintenance deficient 4 , mini chromosome maintenance deficient 4 homolog , minichromosome maintenance deficient 4 homolog , P1-CDC21
GENE ID | SPECIES |
---|---|
448137 | Xenopus (Silurana) tropicalis |
337598 | Danio rerio |
4173 | Homo sapiens |
426764 | Gallus gallus |
477871 | Canis lupus familiaris |
504367 | Bos taurus |
29728 | Rattus norvegicus |
17217 | Mus musculus |
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